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Scar fading hydrophily pressure-sensitive adhesive and preparation method thereof

A technology of hydrophilic pressure-sensitive adhesive and scar reduction. It is applied in the direction of pharmaceutical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. It can solve the problem of poor hydrophobicity of pressure-sensitive adhesives, skin allergies, and sticking parts Water accumulation and other problems, to achieve the effect of high peel strength, strong bactericidal ability, and good water absorption

Inactive Publication Date: 2015-10-07
SUZHOU JONATHAN NEW MATERIALS TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Medical pressure-sensitive adhesives are mainly rubber. This type of pressure-sensitive adhesive is composed of natural or synthetic rubber and various additives. However, this type of pressure-sensitive adhesive has poor hydrophobicity and cannot effectively penetrate water. Whitening and peeling, the added low molecular weight components can cause adverse reactions such as skin allergies

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A hydrophilic pressure-sensitive adhesive for reducing scars, comprising the following components in parts by weight: 15 parts of polyacrylate, 1.5 parts of Scutellaria baicalensis extract, 1 part of citronella essential oil, 55 parts of alginate, and 15 parts of glass fiber , 3 parts of rosin glyceride, 1 part of aloe extract, 0.5 part of ammonium persulfate, 2 parts of sodium edetate, 0.5 part of olive oil, 12 parts of polyethylene glycol.

[0018] The preparation method of the above-mentioned desalination scar hydrophilic pressure-sensitive adhesive comprises the following steps:

[0019] Step 1: Weigh the raw materials according to parts by weight, mix polyacrylate, alginate, glass fiber and polyethylene glycol, put them into an open mill, stir for 5 minutes, and knead at 70°C for 30 minutes to obtain the first mixture;

[0020] Step 2, add Scutellaria baicalensis extract, rosin glyceride, aloe extract, ammonium persulfate and sodium ethylenediamine acetate to the f...

Embodiment 2

[0023] A hydrophilic pressure-sensitive adhesive for reducing scars, comprising the following components in parts by weight: 22-26 parts of polyacrylate, 1.6-1.7 parts of Scutellaria baicalensis extract, 2-3 parts of citronella essential oil, and 58 parts of alginate -62 parts, glass fiber 16-18 parts, rosin glyceride 3.8-4.2 parts, aloe extract 4-6 parts, ammonium persulfate 0.6-0.7 parts, sodium edetate 3-5 parts, olive oil 0.8- 1.0 parts, polyethylene glycol 20-26 parts.

[0024] The preparation method of the above-mentioned desalination scar hydrophilic pressure-sensitive adhesive comprises the following steps:

[0025] Step 1: Weigh the raw materials according to parts by weight, mix polyacrylate, alginate, glass fiber and polyethylene glycol, put them into an open mill, stir for 6 minutes, and knead at 75°C for 35 minutes to obtain the first mixture;

[0026] Step 2, add Scutellaria baicalensis extract, rosin glyceride, aloe extract, ammonium persulfate and sodium ethyl...

Embodiment 3

[0029] A kind of hydrophilic pressure-sensitive adhesive for diluting scars, comprising the following components in parts by weight: 28 parts of polyacrylate, 1.8 parts of Scutellaria baicalensis extract, 4 parts of citronella essential oil, 65 parts of alginate, and 20 parts of glass fiber , 4.5 parts of rosin glyceride, 8 parts of aloe extract, 0.8 parts of ammonium persulfate, 6 parts of sodium edetate, 1.2 parts of olive oil, and 28 parts of polyethylene glycol.

[0030] The preparation method of the above-mentioned desalination scar hydrophilic pressure-sensitive adhesive comprises the following steps:

[0031] Step 1: Weigh the raw materials according to parts by weight, mix polyacrylate, alginate, glass fiber and polyethylene glycol, put them into an open mill, stir for 8 minutes, and knead for 40 minutes at 80°C to obtain the first mixture;

[0032] Step 2, add Scutellaria baicalensis extract, rosin glyceride, aloe extract, ammonium persulfate and sodium ethylenediamin...

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PUM

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Abstract

The invention discloses scar fading hydrophily pressure-sensitive adhesive and a preparation method thereof. The pressure-sensitive adhesive comprises the following components including polyacrylic ester, a scutellaria root extract, cybopogon essential oil, alginate, glass fiber, rosin glycerin ester, an aloe extract, ammonium persulfate, sodium ethylene diamine tetracetate, olive oil and polyethylene glycol. The preparation method comprises the steps that raw materials are weighed by weight, the polyacrylic ester, the alginate, the glass fiber and the polyethylene glycol are mixed and put into an open mill for stirring, and a first mixture is obtained after mixing for 30-40 min; the scutellaria root extract, the rosin glycerin ester, the aloe extract, the ammonium persulfate and the sodium ethylene diamine tetracetate are added into the first mixture to be stirred and heated to 40-50 DEG C to obtain a second mixture; the cybopogon essential oil and the olive oil are mixed and then dropped into the second mixture to be stirred and milled for 35-40 min, and then a slab vulcanizing machine is used to conduct hot pressing to form the pressure-sensitive adhesive with needed thickness. The scar fading hydrophily pressure-sensitive adhesive has the advantages that the glass strength is large, the viscidity is good, and the clinical application value is achieved.

Description

technical field [0001] The invention belongs to the field of medical pressure-sensitive adhesives, and in particular relates to a scar-reducing hydrophilic pressure-sensitive adhesive and a preparation method thereof. Background technique [0002] Pressure-sensitive adhesive is a kind of adhesive that produces viscosity under pressure and leaves no residue after pressure loss, and is the main auxiliary material of transdermal absorption preparations. Medical pressure-sensitive adhesives are mainly rubber. This type of pressure-sensitive adhesive is composed of natural or synthetic rubber and various additives. However, this type of pressure-sensitive adhesive has poor hydrophobicity and cannot effectively penetrate water. Whitening and peeling, the added low molecular weight components can cause adverse reactions such as skin allergies. At present, many researches are devoted to the anti-inflammatory and bactericidal research of pressure-sensitive adhesives. With the improv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/46A61K47/34A61K36/899A61P31/02A61P17/02
Inventor 吕少波李卓才李苏杨
Owner SUZHOU JONATHAN NEW MATERIALS TECH