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Preparation method of codonopsis pilosula chewable tablet for tonifying qi

A technology of chewable tablets and Codonopsis pilosula, applied in the field of preparation of Codonopsis pilosula tonifying chewable tablets, can solve problems such as inconvenient taking, and achieve good tablet properties and improved stability

Inactive Publication Date: 2015-12-23
李康
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the traditional Chinese medicine preparations on the market generally have the problem of inconvenient taking.

Method used

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  • Preparation method of codonopsis pilosula chewable tablet for tonifying qi
  • Preparation method of codonopsis pilosula chewable tablet for tonifying qi

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Step 1, by weight, prepare the following raw materials, 90 parts of Codonopsis pilosula, 10 parts of filler, 5 parts of binder, 4 parts of lubricant, and 6 parts of flavoring agent;

[0025] Step 2. Take the Codonopsis pilosula, add water to suffocate it, drain it, put it in a pressure cooker for cooking, and then fry it. The pressure in the pressure cooker is 0.15MPa; the cooking time is 0.5h; the cooking temperature is 110°C;

[0026] Step 3: decoct the Codonopsis pilosula obtained after frying in water, add 5 times the weight of the raw material Codonopsis pilosula, heat to reflux, decoct for 1 hour, and concentrate the filtrate under reduced pressure until the relative density at 80°C is 1.15, Let cool and adjust the pH to 3 with acetic acid;

[0027] The 4th step, add 3 times of raw material Codonopsis Codonopsis weight ethanol aqueous solution (the mass concentration of ethanol aqueous solution is 70%) in the decoction liquid of the 3rd step gained, stir well; Lea...

Embodiment 2

[0030] Step 1, prepare the following raw materials by weight, 110 parts of Codonopsis pilosula, 20 parts of filler, 8 parts of binder, 7 parts of lubricant, and 12 parts of flavoring agent;

[0031] Step 2: Take the Codonopsis pilosula, add water to suffocate it, drain it, put it in a pressure cooker for cooking, and then fry it. The pressure in the pressure cooker is 0.25MPa; the cooking time is 1.5h; the cooking temperature is 130°C;

[0032] Step 3: decoct the Codonopsis pilosula obtained after frying in water, add water 10 times the weight of the raw material Codonopsis pilosula, heat to reflux, decoct for 3 hours, concentrate the filtrate under reduced pressure until the relative density at 80°C is 1.20, Let cool and adjust the pH to 5 with acetic acid;

[0033] The 4th step, add 5 times of ethanol aqueous solution (the mass concentration of ethanol aqueous solution is 90%) of raw material Codonopsis Codonopsis weight to the decoction liquid of the 3rd step gained, stir; ...

Embodiment 3

[0036] Step 1, in parts by weight, prepare the following raw materials, 100 parts of Codonopsis pilosula, 15 parts of filler, 7 parts of binder, 6 parts of lubricant, and 9 parts of flavoring agent;

[0037] Step 2. Take the Codonopsis pilosula, add water and drain it, put it in a pressure cooker for cooking, and then fry it. The pressure in the pressure cooker is 0.18MPa; the cooking time is 0.8h; the cooking temperature is 115°C;

[0038] Step 3: decoct the Codonopsis pilosula obtained after frying with water, the amount of water added is 8 times the weight of the raw material Codonopsis pilosula, heat to reflux, decoct for 2 hours, and concentrate the filtrate under reduced pressure until the relative density at 80°C is 1.18, Let cool and adjust the pH to 4 with acetic acid;

[0039] The 4th step, add 3~5 times of ethanol aqueous solution (the mass concentration of ethanol aqueous solution is 80%) of raw material Codonopsis Codonopsis weight to the decoction liquid obtained...

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Abstract

The invention discloses a preparation method of a codonopsis pilosula chewable tablet for tonifying qi, and belongs to the technical field of a traditional Chinese medicinal preparation. The preparation method comprises the following steps: preparing codonopsis pilosula and completely soaking the codonopsis pilosula in water, draining off the codonopsis pilosula, cooking the codonopsis pilosula in a pressure cooker and frying the codonopsis pilosula; decocting the codonopsis pilosula obtained from frying in water, heating and refluxing, decompressing and concentrating a filtrate, cooling and regulating pH by virtue of acetic acid; adding an ethanol water solution to an obtained decoction and uniformly stirring; standing by, filtering and reserving supernatant, decompressing and concentrating, recovering ethanol and obtaining a thick paste; and in addition, uniformly mixing a filling agent, a binding agent, a lubricating agent and a flavoring agent with the thick paste, granulating, drying and tabletting so as to obtain the chewable tablet. The codonopsis pilosula chewable tablet prepared by the invention is relatively good in tablet character; and corresponding impurities are removed in the preparation method, so that the stability of lobetyolin is improved after storage.

Description

technical field [0001] The invention discloses a preparation method of Codonopsis pilosula tonifying Qi chewable tablet, which belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Diet therapy is an important part of TCM therapeutics. Under the guidance of this principle, physicians of all dynasties often combined medicine and food in the process of actual clinical prescription. The combination of medicine and food is convenient, safe and effective. [0003] Invigorating qi, also known as replenishing qi. Refers to the method of treating qi deficiency syndrome with qi invigorating drugs. The lung governs qi, and governs the qi of the five internal organs and six internal organs of the body; the spleen and stomach in the middle burner receive water and grains, the spleen is in good circulation, and qi and blood can be metabolized. Therefore, qi deficiency is mostly related to the lungs and spleen. The main symptoms of ...

Claims

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Application Information

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IPC IPC(8): A61K36/344A61K9/20A61P1/04
Inventor 李康
Owner 李康