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Maca ultra-micro wall breaking and crushing method

A technology of ultra-fine wall-breaking crushing and maca powder, which is applied in the field of medicine, can solve the problems of low powder yield, long crushing time, high loss rate of N-benzyl-hexadecanamide, etc., and achieve high powder yield, The effect of short processing time

Inactive Publication Date: 2016-02-17
SUZHOU PULUODA BIOLOGICAL SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing maca ultrafine wall-breaking pulverization method has problems such as long pulverization time, low powder yield and high loss rate of N-benzyl-hexadecanamide

Method used

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  • Maca ultra-micro wall breaking and crushing method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] 3kg of maca is pulverized and passed through a 60-80 mesh sieve to obtain maca powder; 8g of porous starch and 2g of medium-chain triglyceride are mixed evenly to obtain a porous starch-medium-chain triglyceride mixed powder; maca powder and porous The starch-medium-chain triglyceride mixed powder is mixed evenly, and crushed by SWFJ ultrafine pulverizer for 1 hour. The obtained powder is measured for average particle size, powder yield, N-benzyl-hexadecanamide retention rate and dissolution rate. The results are shown in Table 1.

[0017] The maca superfine powder relevant data of table 1 embodiment 1

[0018]

Embodiment 2

[0020] 3kg of maca is pulverized and passed through a 60-80 mesh sieve to obtain maca powder; 12g of porous starch and 3g of medium-chain triglyceride are mixed evenly to obtain a porous starch-medium-chain triglyceride mixed powder; maca powder and porous The starch-medium-chain triglyceride mixed powder is mixed evenly, and crushed by SWFJ ultrafine pulverizer for 1 hour. The obtained powder is measured for average particle size, powder yield, N-benzyl-hexadecanamide retention rate and dissolution rate. The results are shown in Table 2.

[0021] The maca superfine powder relevant data of table 2 embodiment 2

[0022]

Embodiment 3

[0024] 3kg of maca was pulverized and passed through a 60-80 mesh sieve to obtain maca powder; 9.6g of porous starch and 2.4g of medium-chain triglyceride were mixed uniformly to obtain a porous starch-medium-chain triglyceride mixed powder; Mix evenly with porous starch-medium chain triglyceride mixed powder, and use SWFJ ultrafine pulverizer to pulverize for 1 hour, and measure the average particle size, powder yield, N-benzyl-hexadecanamide retention rate and dissolution rate of the obtained powder. The results are shown in Table 3.

[0025] The maca superfine powder relevant data of table 3 embodiment 3

[0026]

[0027]

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Abstract

The invention provides a maca ultra-micro wall breaking and crushing method and belongs to the field of traditional Chinese medicines. The maca ultra-micro wall breaking and crushing method is characterized by comprising the following steps: (1) crushing maca and sieving the maca with a sieve of 60-80 meshes to obtain maca powder; (2) uniformly mixing porous starch and medium-chain triglyceride to obtain porous starch-medium-chain triglyceride mixed powder, wherein preferably, the mass ratio of the porous starch to the medium-chain triglyceride is 8 to 2; (3) uniformly mixing the maca powder with the porous starch-medium-chain triglyceride mixed powder, wherein preferably, the mass ratio of the maca powder to the porous starch-medium-chain triglyceride mixed powder is (300-200) to 1. Compared with a conventional ultra-micro wall breaking and crushing method, the maca ultra-micro wall breaking and crushing method provided by the invention has the advantages of short machining time, high powder yield, high retention rate and dissolution rate of N-benzyl hexadecanamide, small average grain diameter of the powder and the like.

Description

technical field [0001] The invention relates to a method for ultrafine wall-breaking and crushing of maca, which belongs to the technical field of medicine. Background technique [0002] Maca has a good nourishing and strengthening effect on the human body, and it is often used in powder form. [0003] After the maca is ultrafinely pulverized, due to the increase in the specific surface area of ​​the particle size, the dissolution rate of active ingredients such as N-benzyl-hexadecanamide can be greatly increased, thereby improving the drug effect. The existing maca ultrafine wall-breaking pulverization method has problems such as long pulverization time, low powder yield and high loss rate of N-benzyl-hexadecanamide. Contents of the invention [0004] The purpose of the present invention is to provide a kind of maca ultrafine wall-broken pulverization method, to solve the above-mentioned technical problem. [0005] For the purpose of the above invention, the present inv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A61K9/14A61K47/36A61K47/14A61P1/14A61P39/00
Inventor 罗瑞雪张振海
Owner SUZHOU PULUODA BIOLOGICAL SCI & TECH