A cigarette fingerprint analysis method based on gc-msqqq

Abstract

The invention discloses a cigarette fingerprint spectrum analysis method based on GC-MSQQQ (gas chromatography-triple tandem quadrupole mass spectrometry). The stability of inherent quality of a cigarette is determined through solvent extraction of a cigarette sample, obtaining of a GC-MSQQQ fingerprint spectrum as well as calculation and analysis of included angle cosine and the Euclidean distance. The method has the characteristics that as for characteristic aroma components of the cigarette, firstly, detection is performed in a full scan mode after supersonic extraction, 29 components with the highest content are qualitatively analyzed, then, an MRM (multiple reaction monitoring) detection method is established for quantitative analysis, and acquired fingerprint spectrum baselines are stable, the separation degree is high, and the quantitation is more accurate. The stability of inherent quality of the cigarette can be reflected objectively, the method is an effective supplement to conventional manual smoke sensory quality evaluation methods, the evaluation is more scientific, the product quality is stabilized, and a technical support is provided for consistency of quality of products processed in different places.

Description

technical field [0001] The invention relates to the field of cigarette testing, in particular to a method for analyzing cigarette fingerprints based on GC-MSQQQ. Background technique [0002] In recent years, various modern instrumental analysis methods such as GC / MS, HPLC and HPLC / MS have become commonly used methods in the study of fingerprints. They have the advantages of high separation efficiency, fast analysis speed, and good stability. Common and effective methods. [0003] The document with the application number 201110365633.9 relates to a method for establishing a GC / MS fingerprint of flue-cured tobacco and its application. It adopts ultrapure water system simultaneous distillation and extraction method for extraction and GC / MS detection to obtain GC / MS fingerprints with good baseline separation, many characteristic peaks and high peak responsivity. The established flue-cured tobacco GC / MS fingerprint and its supporting analysis technology were applied to the qua...

AI Technical Summary

Problems solved by technology

[0006] The above-mentioned patent documents all pay attention to the integrity of the sample, conduct a full scan of the sample components, and then perform quantitative analysis on the common peaks in it. However, due to the complexity of the sample matrix such as cigarettes, the baseline is not stable, and some components interfere with the common peaks, resulting in quantitative analysis. Inaccurate, affecting the accuracy of fingerprint data analysis

With the development of modern analysis technology, the application of GC-MSQQQ will make the research methods of fingerprints more diversified, especially it has many advantages such as stable baseline, good selectivity, and ability to effectively eliminate interference. Unique advantages, but there is no report on its use in cigarette fingerprint research

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