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Pharmaceutical composition capable of treating cerebral thrombosis and preparation method of pharmaceutical composition

A technology of composition and cerebral thrombosis, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve unsatisfactory problems

Inactive Publication Date: 2016-10-26
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, oral drugs for treating cerebral thrombosis mainly include: Nao Xue Shuan Tablets, Xuesai Tong, Da Huo Luo Dan, etc. Although these drugs have certain curative effects, they are still unsatisfactory.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of cerebral thrombosis

[0034]The composition and parts by weight of the raw materials of the pharmaceutical composition for treating cerebral thrombosis are: 600 parts by weight of wild clove root, 1100 parts by weight of madder vine, 2300 parts by weight of hemlock, 3200 parts by weight of toosendan, 3700 parts by weight of side seeds, soft 107 parts by weight of sitosterol fatty acid, 62 parts by weight of wood tannin C;

[0035] Preparation:

[0036] (1) Take wild clove root, madder vine, hemlock, toosendan, side seed, sitosterol palmitate, and wood tannin C according to the ratio of raw materials, mix well, and use ethanol with a concentration of 33% by weight as a solvent , at 45°C for warm soaking and extraction, the number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 33 times the total weight of the raw mater...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for the treatment of cerebral thrombosis and its preparation method

[0040] The composition and parts by weight of the raw material drug of the pharmaceutical composition for treating cerebral thrombosis are: 550 parts by weight of clove root, 1150 parts by weight of madder vine, 2250 parts by weight of hemlock, 3250 parts by weight of toosendan, 3650 parts by weight of side seeds, soft 112 parts by weight of sitosterol fatty acid, 58 parts by weight of wood tannin C;

[0041] Preparation:

[0042] (1) Take wild clove root, madder vine, hemlock, toosendan, side seed, sitosterol palmitate, and wood tannin C according to the ratio of raw materials, mix well, and use ethanol with a concentration of 33% by weight as a solvent , at 45°C for warm soaking and extraction, the number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 33 times the total weight of the raw material ...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition for the treatment of cerebral thrombosis and its preparation method

[0046] The composition and parts by weight of the raw materials of the pharmaceutical composition for treating cerebral thrombosis are: 650 parts by weight of wild clove root, 1050 parts by weight of madder vine, 2350 parts by weight of hemlock, 3150 parts by weight of toosendan, 3750 parts by weight of side seeds, soft Sitosteryl fatty acid 102 parts by weight, wood tannin C68 parts by weight;

[0047] Preparation:

[0048] (1) Take wild clove root, madder vine, hemlock, toosendan, side seed, sitosterol palmitate, and wood tannin C according to the ratio of raw materials, mix well, and use ethanol with a concentration of 33% by weight as a solvent , at 45°C for warm soaking and extraction, the number of extractions is 9 times, each extraction time is 38 hours, and the amount of solvent used each time is 33 times the total weight of the raw material drug, ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition capable of treating cerebral thrombosis and a preparation method of the pharmaceutical composition. The pharmaceutical composition disclosed by the invention is prepared by taking roots of intermediate luculia, stems and leaves of India madder, european waterhemlock roots, Szechwan chinaberry fruits, branch monkshood daughter, palmitic acid sitosterol ester and cornusiin C as raw drugs through proportioning. The pharmaceutical composition can be prepared into various types of preparations according to a conventional preparation process and has a remarkable curative effect on treatment of cerebral thrombosis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating cerebral thrombosis and a preparation method thereof. Background technique [0002] The definition of cerebral thrombosis is that various factors cause vascular wall lesions, resulting in cerebral artery lumen occlusion, stenosis, blood flow reduction, resulting in a state of ischemia and hypoxia, showing a focal nervous system symptom, more males Yu female. It has high morbidity, disability and mortality, which seriously affects the quality of life of patients. [0003] Western medicine treatment is divided into conservative treatment and surgical treatment. Conservative treatment mainly uses intravenous infusion of thrombolytics, although good short-term effects have been achieved, but it is easy to repeat; surgical treatment is extremely risky. At present, oral medicines for the treatment of cerebral thrombosis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/74A61P9/10A61K31/575A61K31/7024
CPCA61K36/74A61K31/575A61K31/7024A61K36/23A61K36/58A61K36/714A61K2236/333A61K2236/39A61K2236/51A61K2236/55
Inventor 庞大坤孔倩倩
Owner JINAN XINGYI MEDICAL TECH