Colloidal gold immunochromatography five-joint diagnostic reagent kit for salmonella infection

Abstract

The invention discloses a colloidal gold immunochromatography five-joint diagnostic reagent kit for salmonella infection. The colloidal gold immunochromatography five-joint diagnostic reagent kit is mainly characterized by comprising a box seat; a horizontal groove is formed in the front end of the box seat, five vertical positioning grooves are transversely formed in the box seat at intervals, two ends of each of left barriers and right barriers of the vertical positioning grooves are respectively fixedly connected with a rear barrier of the corresponding groove and a rear barrier of the box seat, openings are formed in the centers of the vertical positioning grooves and a public barrier of the grooves, and reaction cards are fixed into the positioning grooves and include a reaction card for detecting typhoid bacillus O antibodies, a reaction card for detecting typhoid bacillus H antibodies, a reaction card for detecting bacillus paratyphosus A antibodies, a reaction card for detecting bacillus paratyphosus B antibodies and a reaction card for detecting salmonella antigens. The colloidal gold immunochromatography five-joint diagnostic reagent kit has the advantages that immunological methods and colloidal gold labeling technologies are organically combined with one another, and accordingly the time-saving, labor-saving, safe and speedy colloidal gold immunochromatography five-joint diagnostic reagent kit which is high in specificity can be conveniently widely applied to diagnosing salmonella infection.

Description

technical field [0001] The invention belongs to the field of medical diagnosis, and specifically refers to a colloidal gold immunochromatographic five-unit diagnostic kit for Salmonella infection. Background technique [0002] Salmonella is widely distributed in nature, and has a wide range of hosts in humans and animals. Humans are pathogenic. The clinical manifestations of Salmonella infection are gastroenteritis type, typhoid type, sepsis type and local suppurative infection type. This disease is prevalent in various degrees in all countries in the world, and can be suffered at any age. Young people (especially those who are about 1 year old) ), the elderly, those with chronic wasting diseases and those who have taken antibacterial drugs in the near future are more susceptible. [0003] Salmonella infection is easily misdiagnosed as gastrointestinal disease, typhoid fever, blood disease or other diseases, which delays the best time for treatment. Inquiry about eating h...

AI Technical Summary

Problems solved by technology

[0004] At present, the detection methods for Salmonella infection are laboratory detection, mainly including bacterial culture, Veta reaction in serological reaction, immunological methods (ELISA, DotELISA, Dipstick assay), polymerase chain reaction (PCR), etc. Bacterial culture and Vita reaction are widely used in the prior art. Others have not been promoted clinically due to imperfect technology or operational problems. However, bacterial culture and Vita reaction still have great disadvantages: the reaction time is long, and the results cannot be obtained. Slow reporting, expensive instruments and equipment, strict testing environment, cumbersome operation, low specificity, poor safety, difficulty in judging negative and positive results, inaccurate clinical analysis, etc.

[0005] Colloidal gold immunochromatography is a mature labeling technology, which can be used to label a variety of antigens and antibodies at present, but it is used to label Salmonella antigens and antibodies, which can be combined to diagnose typhoid, paratyphoid A, paratyphoid B and Salmonella The five-unit kit for Bacteria infection has not been reported yet, and the present invention fills up a blank for the development of this technical field

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