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Preparation method of medicinal fermented calcium carbonate

A calcium carbonate and pharmaceutical technology, applied in the field of preparation of pharmaceutical fermented calcium carbonate, can solve the problems of difficult calcium carbonate, unstable free alkali content, etc., and achieve the effect of uniform particle size

Active Publication Date: 2019-01-11
石家庄市东升钙业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention proposes a method for preparing medical fermented calcium carbonate, which solves the technical problems in the prior art that it is difficult to produce medical fermented calcium carbonate with low free alkali content and the free alkali content is unstable

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  • Preparation method of medicinal fermented calcium carbonate
  • Preparation method of medicinal fermented calcium carbonate
  • Preparation method of medicinal fermented calcium carbonate

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preparation example Construction

[0024] Such as figure 1 Shown, the preparation method of the pharmaceutical fermented calcium carbonate that the present invention proposes may further comprise the steps:

[0025] Digestion: raw limestone is added to water for digestion;

[0026] Primary aging: the digested slurry is subjected to primary aging until the calcium oxide in the slurry is completely decomposed;

[0027] Primary carbonization: the slurry is carbonized once;

[0028] Secondary aging: After the primary carbonization is stopped, the slurry is subjected to secondary aging;

[0029] Secondary carbonization: After the aging is completed, sucrose is added to the slurry to start the second carbonization, and dilute phosphoric acid is added during the carbonization for another 10 minutes.

[0030] Further, the primary carbonization in the primary carbonization step stops when the pH value of the slurry reaches 8.0-9.0.

[0031] Further, dilute phosphoric acid is added when the pH value of the slurry rea...

Embodiment 1

[0038] Add 100°C hot water to the raw material (limestone) to digest it, and then place the digested slurry in the slurry storage tank for an aging time of 6 hours to ensure that all calcium oxide is fully decomposed. Carry out carbonization treatment to slurry afterwards, and carbonization treatment is divided into primary carbonization and secondary carbonization, and primary carbonization stops when slurry pH value reaches 9.0, then puts slurry in the storage tank for secondary aging, aging time is 8 hours, The slurry is then subjected to secondary carbonization.

[0039] During the secondary carbonization, first add a certain amount of sucrose to the slurry, the amount added is 0.1% of the total weight of the limestone to be produced, and when the slurry is carbonized to a pH value of 7.5, the ratio is 1:2000 (dilute phosphoric acid: slurry) Add 45% dilute phosphoric acid to the slurry, stir evenly and then carbonize for 10 minutes, then dry and other follow-up treatments ...

Embodiment 2

[0041] Add 100°C hot water to the raw material (limestone) to digest it, and then place the digested slurry in the slurry storage tank for an aging time of 6 hours to ensure that all calcium oxide is fully decomposed. Carry out carbonization treatment to slurry afterwards, and carbonization treatment is divided into primary carbonization and secondary carbonization, and primary carbonization stops when slurry pH value reaches 9.0, then puts slurry in the storage tank for secondary aging, aging time is 8 hours, The slurry is then subjected to secondary carbonization.

[0042] During the secondary carbonization, first add a certain amount of sucrose to the slurry, the amount added is 0.1% of the total weight of the limestone to be produced, and when the slurry is carbonized to a pH value of 7.5, the ratio is 1:2000 (dilute phosphoric acid: slurry) Add dilute phosphoric acid with a concentration of 48% to the slurry, stir evenly and then carbonize for 10 minutes, then dry and oth...

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Abstract

The invention belongs to the technical field of calcium carbonate preparations and provides a preparing method of medicine fermenting calcium carbonate. The preparing method comprises the steps of digesting, digesting raw material limestone by adding water; conducting a first aging, conducting the first aging to the digested slurry until calcium oxide in the slurry is completely decomposed; conducting a first carbonization, conducting the first carbonization to the slurry; conducting a second aging, conducting the second aging to the slurry after the first carbonization ends; conducting a second carbonization, adding cane sugar into the slurry after the aging finishes and conducting the second carbonization, during which, adding diluted phosphoric acid to carbonize for another 10 minutes; in the step of the first carbonization, ending the first carbonization when PH value of the slurry reaches 8.0-9.0; in the step of the second carbonization, adding the diluted phosphoric acid when PH value of the slurry reaches 7.5; in the step of the second carbonization, the additive amount of the cane sugar is 0.1%-0.5% of the total weight of the limestone. According to the preparing method of medicine fermenting calcium carbonate, an ingenious concept is adopted, and the technical problems that producing medicine fermenting calcium carbonate with low content of free alkali is difficult and the content of free alkali is unstable in prior art are resolved.

Description

technical field [0001] The invention belongs to the technical field of calcium carbonate preparation, and relates to a method for preparing medicinal fermented calcium carbonate. Background technique [0002] The core of pharmaceutical fermented calcium carbonate is to obtain the low free alkali content of the product. At present, the alkalinity of our products is measured by the pH value. In fact, the pH value does not fully explain the level of its alkalinity. Calcium carbonate is a weak base. Generally speaking, when the pH value reaches 9.5-10 and the free base reaches 0.1, it can meet the processing requirements of general industrial products. However, the free base content is required to be no more than 0.01 during the preparation of pharmaceutical fermented calcium carbonate, which greatly enhances the difficulty of production. And it is difficult to maintain the stability of its content. Contents of the invention [0003] The invention proposes a preparation metho...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C01F11/18
CPCC01F11/181C01P2006/90
Inventor 康和义
Owner 石家庄市东升钙业有限公司