Gene sequencer, automatic leveling device and method

Abstract

A genetic sequencer, and an automatic levelling apparatus and method. The automatic levelling apparatus is used for levelling a sequencing reaction chamber (1), and comprises an installation platform (10), a levelling board (20), at least one rotary mechanism (30), at least one driving mechanism (40), an image collection apparatus (50) and a control apparatus. The levelling board (20) comprises a rotary fulcrum portion connected to the rotary mechanism (30) and enabling the levelling board (20) to be integrally rotatably arranged on the installation platform (10), and a rotary driving portion connected to the driving mechanism (40); the image collection apparatus (50) is arranged corresponding to the sequencing reaction chamber (1), and collects distance information between at least two position points of a reaction channel (100) of the sequencing reaction chamber (1) and the image collection apparatus (50); and the control apparatus is in communication connection with the image collection apparatus (50) and the driving mechanism (40), and outputs a control signal according to the distance information collected by the image collection apparatus (50), so that the driving mechanism (40) is controlled to drive the levelling board (20) to rotate, and the at least two position points of the reaction channel (100) have consistent distances from the image collection apparatus (50) or have a distance difference value within a pre-set range. The present invention achieves automatic levelling and has high efficiency.

Description

technical field [0001] The invention relates to the field of gene sequencing, in particular to a gene sequencer, an automatic leveling device and a method. Background technique [0002] Gene sequencing technology uses a gene sequencer to detect nucleic acids, and obtains nucleic acid sequences through data processing. The sequencing process of the current gene sequencer is composed of a series of mechanical, electronic communication, biological, chemical, optical and other operations. The DNA fragment sample to be tested is set in the reaction chamber of the gene sequencer for sequencing reaction. The reaction channel flows through the sequencing reaction chamber to generate a sequencing reaction with the sample to be tested. After the sequencing reaction is completed, the sequencing image is collected by the image acquisition device, and the gene sequence is obtained after post-processing. [0003] Since gene sequencing requires very high precision, which belongs to the m...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a gene sequencer, automatic leveling device and method, aiming to solve the technical problems of low leveling automation and low efficiency in the prior art

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