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Drug containing Volvalerelactone A and used for healing scald

A drug, a technology that acts as a drug glycoside, is applied in the field of medicine and can solve problems such as affecting limb function and long-term non-healing

Inactive Publication Date: 2017-04-19
徐州诺克非医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If the wound is not treated in time, it will not heal for a long time due to infection, resulting in scarring and affecting limb function
[0003] The compound Volvalerelactone A was published in 2011 (Peng-Cheng Wang, et al., Volvalerelactone A and B, Two New Sesquiter penoid Lactones with an Unprecedented Skeleton from Valeriana officinalis var. latifolia. Organic Letters, 2011, 13(12), 3036–3039 .) is a new compound, which has a brand-new skeleton type, and there are no reports about Volvalerelactone A and Dangyaoside being used to heal scalds

Method used

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  • Drug containing Volvalerelactone A and used for healing scald
  • Drug containing Volvalerelactone A and used for healing scald

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Experimental program
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Effect test

Embodiment Construction

[0012] The above description is only an overview of the technical solution of the present invention. In order to understand the technical means of the present invention more clearly and implement it according to the content of the description and conventional technical means in the field, the animal test examples of the present invention will be further described in detail below .

[0013] Chinese name: Dangyaoside CAS number: 14215-86-2, sold by Chengdu Zhibiao Huachun Biotechnology Co., Ltd.

[0014] The preparation method of compound Volvalerelactone A involved in the present invention is referred to literature: (Peng-ChengWang, et al., Volvalerelactone A and B, Two New Sesquiter penoid Lactones with an Unprecedented Skeleton from Valeriana officinalis var. latifolia. Organic Letters, 2011,13 (12) , 3036–3039.).

[0015] Rat test:

[0016] Modeling: mice, female, weighing 18-22g. The ambient temperature of the animal room is 25°C-28°C, and the humidity is 35%-45%. 210 m...

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Abstract

The invention discloses a drug containing Volvalerelactone A and used for healing scald; effective components include Volvalerelactone A and also include chiratin. Through combined application of Volvalerelactone A and chiratin, experimental results show that when the ratio of Volvalerelactone A to chiratin is 15:1-18:1, the drug has good effects on healing scald.

Description

technical field [0001] The invention relates to a medicine containing Volvalerelactone A for healing scalds, which belongs to the technical field of medicine. Background technique [0002] Burns and scalds are a complex surgical disease caused by the action of boiling water, boiling oil, fire, electricity, or acid-base substances on human skin. Generally, fire burns and boiling water or oil burns are common. Mild burns or scalds cause redness, swelling, burning pain or blisters on the epidermis; severe burns and scalds, due to damage to human skin and subcutaneous tissue, fire and poison damage and Yin fluid in the body, attack viscera internally, damage Yin and Yang, often lead to Water and electrolyte imbalance, shock, skin tissue redness, ulceration, infection and other serious consequences. If the wound is not treated in time, it will not heal for a long time due to infection, resulting in scarring and affecting limb function. [0003] The compound Volvalerelactone A w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/366A61P17/02
CPCA61K31/366A61K31/7048
Inventor 李克道
Owner 徐州诺克非医药科技有限公司