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Preparation process for agent for treating gout

A production process and technology for pharmaceuticals, applied in the fields of food and medicine, can solve the problems of insignificant effect, large liver damage, involvement of internal organs such as kidneys, etc., and achieve the effects of convenient preparation, low harm and good efficacy.

Inactive Publication Date: 2017-05-17
史萍国
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, joint symptoms are often the first manifestation, and may involve internal organs such as the kidney (Huang Yanhong, Lv Yanwei, Clinical Risk Logistio Research Chinese General Practice 2010.1, Vol. 13, No. 1A, 52-56); at this stage, colchicine, other Purine and other drugs are used in combination to treat gout. In the folks, there is a report on the treatment of gout with a combination of drugs such as Desmodium moss (Anargul. Mahmut Nurmamat. Amat. Research progress of natural medicines in the treatment of gout Chinese Journal of Ethnic Medicine 2008.8, No. 8, 45-48). But these treatments either cause serious damage to the liver, or have little effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] A preparation process of a medicine for treating gout, the processing process comprising:

[0016] (1) Using broad bean plants, seeds or broad bean skins and broad bean shells as raw materials, the proportioning combination of raw materials is: broad bean skin 35%, broad bean shell 65%.

[0017] (2) adopt ethanol extraction;

[0018] (3) After the ethanol is recovered, it is processed into dosage forms and forms that are convenient to take.

Embodiment 2

[0020] A preparation process of a medicine for treating gout, the processing process comprising:

[0021] (1) Using broad bean plants, seeds or broad bean skins and broad bean shells as raw materials, the proportioning combination of raw materials is: 65% of broad bean plants and 35% of seeds;

[0022] (2) adopt 75% ethanol to extract;

[0023] (3) After the ethanol is recovered, it is processed into dosage forms and forms that are convenient to take.

Embodiment 3

[0025] A preparation process of a medicine for treating gout, the processing process comprising:

[0026] (1) Taking broad bean plants, seeds or broad bean skins and broad bean shells as raw materials, the proportioning combination of raw materials is: broad bean skin 55%, broad bean shell 45%;

[0027] (2) adopt aqueous acetic acid to extract;

[0028] (3) After the pH value is adjusted to cause alkaline precipitation (or insoluble matter), the solvent for pH adjustment adopts potassium dihydrogen phosphate and potassium hydroxide buffer system, and is processed into dosage forms and forms that are convenient for taking.

[0029] The samples of each embodiment are taken for detection and analysis, and compared with the prior art, the following data are obtained:

[0030] flavonoid content Alkaloid content The level of side effects Active ingredients Example 1 1.05g / kg 2.15g / kg Low flavonoids, alkaloids Example 2 0.94g / kg 1.77g / kg Low ...

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PUM

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Abstract

The invention discloses a preparation process for an agent for treating gout, which includes the following steps: the plant, seeds, broad bean coat and broad been skin of broad beans are adopted as materials, and are extracted by methanol or ethanol or acid aqueous solution and the like, and the agent is used for treating gout. The agent for treating gout prepared by the process utilizes the natural broad bean products as the materials, has good efficacy and no side effects, and is more suitable for use by patients.

Description

technical field [0001] The invention relates to the fields of medicine and food, in particular to a preparation process of a medicine for treating gout. Background technique [0002] Gout is a group of diseases that cause tissue and organ damage due to abnormal purine metabolism. Clinically, joint symptoms are often the first manifestation, and may involve internal organs such as the kidney (Huang Yanhong, Lu Yanwei, Clinical Risk Logistio Research Chinese General Practice 2010.1 Volume 13, Phase 1A 52-56); at this stage, colchicine, other Purine alcohol and other drugs are used in combination to treat gout. In the folks, it is reported that the drug mixed with money grass and other drugs is used to treat gout (Anaerguli. 2008.8, No. 8, 45-48). However, these treatments either cause serious damage to the liver, or have little effect. Through a large number of excavations of ethnic medicines in our province, we found that Yi people have a method of using broad bean shells a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P19/06
CPCA61K36/48A61K2236/333
Inventor 史萍国
Owner 史萍国