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Lucid ganoderma-Coriolus versicolor dripping pill and preparation method thereof

A technology of dripping pills and ganoderma lucidum, applied in the field of Lingyun dripping pills and its preparation, can solve the problems of slow disintegration, affecting curative effect, inactivation of active ingredients and the like

Inactive Publication Date: 2017-09-15
王丽荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are a lot of active proteins and biological peptides in Ganoderma lucidum and Yunzhi. The active ingredients are inactivated in the traditional extraction, and their efficacy cannot be fully exerted. Moreover, the active ingredients cannot be fully dissolved when made into traditional dosage forms, and the disintegration is slow, and the bioavailability is low. curative effect

Method used

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  • Lucid ganoderma-Coriolus versicolor dripping pill and preparation method thereof
  • Lucid ganoderma-Coriolus versicolor dripping pill and preparation method thereof
  • Lucid ganoderma-Coriolus versicolor dripping pill and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0015] Take 90g of Ganoderma lucidum, 40g of Yunzhi, crushed into 40 mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 20Mpa, extraction temperature 25°C, separator pressure 12Mpa, separator temperature 35°C, carbon dioxide flow rate 20L per hour, separation The time was 1 hour to obtain the extraction solution; the extraction solution was placed in a jet spray dryer, and the inlet air temperature was controlled to 25°C, the pressure was 0.02Mpa, and the flow rate was 400 meters per second to obtain nano-extraction powder; the extraction powder was added with 1 times the amount of polyethylene glycol. Mix alcohol 6000, control the material temperature to 60°C, the condensation temperature to 2°C, the drop distance to 2.0 cm, the drop rate of 20 drops per minute, drop into the liquid paraffin, take out the drop pellets after forming, absorb the surface coolant, and decompress at 60°C. After drying, Lingyun Dropping Pills are obtained. ...

specific Embodiment 2

[0017] Take 110g of Ganoderma lucidum, 60g of Yunzhi, crushed into 40 mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 30Mpa, extraction temperature 35°C, separator pressure 18Mpa, separator temperature 45°C, carbon dioxide flow rate 30L per hour, separation The time was 1 hour to obtain the extract; the extract was placed in a jet spray dryer, and the inlet air temperature was controlled to 35°C, the pressure was 0.04Mpa, and the flow rate was 600 meters per second to obtain nano-extraction powder; the extraction powder was added with 2 times the amount of polyethylene Mix well with alcohol 6000, control the material temperature to 70℃, the condensation temperature to 6℃, the drop distance to 4.0cm, the drop rate of 30 drops per minute, drop into the liquid paraffin, take out the drop pills after forming, absorb the surface coolant, and decompress at 60℃ After drying, Lingyun Dropping Pills are obtained.

Embodiment 3

[0019] Take 100g of Ganoderma lucidum, 50g of Yunzhi, crushed into 40 mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 25Mpa, extraction temperature 30°C, separator pressure 15Mpa, separator temperature 40°C, carbon dioxide flow rate 25L per hour, separation The time was 1 hour to obtain the extraction solution; the extraction solution was placed in a jet spray dryer, and the inlet air temperature was controlled to 30°C, the pressure was 0.03Mpa, and the flow rate was 500 meters per second to obtain nano-extraction powder; add 2 times the amount of polyethylene to the extraction powder. Mix alcohol 6000, control the material temperature to 65°C, the condensation temperature to 3°C, the drop distance to 3.0 cm, the drop rate of 25 drops per minute, drop into the liquid paraffin, take out the drop pellets after forming, absorb the surface coolant, and decompress at 60°C. After drying, Lingyun Dropping Pills are obtained.

[0020] The ...

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Abstract

The invention discloses a Lucid ganoderma-Coriolus versicolor dripping pill and a preparation method thereof. The preparation method comprises the following steps: extracting Lucid ganoderma and Coriolus versicolor by using a carbon dioxide supercritical extraction method; then carrying out jet spray drying to prepare nanometer powder; adding polyethylene glycol; and adding a mixture obtained in the previous step into liquid paraffin so as to prepare the Lucid ganoderma-Coriolus versicolor dripping pill. The Lucid ganoderma-Coriolus versicolor dripping pill is applied to treatment of hepatitis, has substantially better curative effect than classic liver-treating drugs and produces good effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a Lingyun dripping pill and a preparation method thereof. Background technique [0002] Ganoderma lucidum is the dry fruiting body of Polyporaceae fungi Ganoderma lucidum or purple lucidum. It has the effects of invigorating qi and calming the nerves, relieving cough and relieving asthma. Yunzhi is the dried fruiting body of Polyporaceae fungus C. versicolor. It has the effects of strengthening the spleen and removing dampness, clearing away heat and detoxifying, and is used for damp-heat jaundice, hypochondral pain, fatigue and fatigue. Ganoderma lucidum and Yunzhi, as traditional precious medicinal materials in China, have high medicinal value, which can enhance human immunity, regulate blood sugar, control blood pressure, and protect liver and liver. There are a lot of active proteins and biological polypeptides in Ganoderma lucidum and Yunzhi. The active ingredie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/074A61K9/20A61K47/10A61P1/16
CPCA61K9/2031A61K36/07A61K36/074A61K2236/37A61K2300/00
Inventor 殷作群朱叶彤
Owner 王丽荣