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A kind of dendrobium buccal tablet and preparation method thereof

The technology of dendrobium and menthol is applied in the field of dendrobium lozenges and their preparation, which can solve the problems of adverse reactions, poor drug efficacy, and inability to fully exert drug efficacy, and achieve the effect of a reasonable production process.

Active Publication Date: 2020-11-13
海南诗博丽生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are also the following problems in the buccal tablets of traditional Chinese medicine: 1. The compatibility of traditional Chinese medicine is unreasonable, and the drug effect is not good; Edible, overdose causes adverse reactions; 3 The preparation method is not refined enough to fully exert the drug effect

Method used

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  • A kind of dendrobium buccal tablet and preparation method thereof
  • A kind of dendrobium buccal tablet and preparation method thereof
  • A kind of dendrobium buccal tablet and preparation method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0024] A dendrobium buccal tablet, consisting of the following components (parts by weight): 200 parts of Dendrobium officinale, 26 parts of menthol, 20 parts of sealwort, 22 parts of honeysuckle, 5 parts of sorbitol, 15 parts of chitosan, 6 parts of glycerin, malt 8 parts of dextrin, 30 parts of magnesium stearate.

[0025] The preparation method is as follows:

[0026] (1) a, take by weighing the dendrobium of noble dendrobium, sealwort and honeysuckle of recipe quantity, pulverize, cross 400 mesh sieves, get superfine powder, adopt 40% ethanol aqueous solution to extract, extract decompression evaporates ethanol, obtain extract and after extraction Medicinal dregs; b, putting the extract of step a on the macroporous resin column, and eluting with distilled water and lye successively; wherein, the distilled water eluent is effluent A; eluted with lye to obtain effluent B; effluent B is used Neutralize the acid to neutral, extract with 40% ethanol aqueous solution for 3 hour...

Embodiment 2

[0030] A dendrobium buccal tablet, consisting of the following components (parts by weight): 180 parts of Dendrobium nobile, 12 parts of menthol, 18 parts of sealwort, 17 parts of honeysuckle, 5 parts of sorbitol, 12 parts of chitosan, 2 parts of glycerin, 8 parts of maltodextrin, 23 parts of magnesium stearate.

[0031] The preparation method is as follows:

[0032] (1) a, take by weighing the dendrobium of noble dendrobium, sealwort and honeysuckle of recipe quantity, pulverize, cross 500 mesh sieves, get superfine powder, adopt 45% ethanol aqueous solution to extract, extract decompression evaporates ethanol, obtain extract and after extraction Medicinal dregs; b, putting the extract of step a on the macroporous resin column, and eluting with distilled water and lye successively; wherein, the distilled water eluent is effluent A; eluted with lye to obtain effluent B; effluent B is used Neutralize the acid to neutral, extract with 50% ethanol aqueous solution for 1.5h, and ...

Embodiment 3

[0036] A dendrobium buccal tablet, consisting of the following components (parts by weight): 235 parts of Dendrobium Huoshanense, 26 parts of menthol, 28 parts of sealwort, 22 parts of honeysuckle, 7 parts of sorbitol, 15 parts of chitosan, 6 parts of glycerin, malt 12 parts of dextrin, 40 parts of magnesium stearate.

[0037] The preparation method is as follows:

[0038] (1) a, take by weighing the dendrobium of noble dendrobium, Rhizoma Polygonatum and Flos Lonicerae Flos Lonicerae of prescription, pulverize, cross 450 mesh sieves, obtain superfine powder, adopt 45% ethanol aqueous solution to extract, extract decompression evaporates ethanol, obtain extract and after extracting Medicinal dregs; b, putting the extract of step a on the macroporous resin column, and eluting with distilled water and lye successively; wherein, the distilled water eluent is effluent A; eluted with lye to obtain effluent B; effluent B is used Neutralize the acid to neutral, extract with 45% etha...

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Abstract

The invention belongs to the technical field of drug processing and particularly relates to a dendrobium lozenge and a preparation method thereof. The dendrobium lozenge is prepared from the following raw materials in parts by weight: 180-235 parts of dendrobium, 12-26 parts of menthol, 18-28 parts of polygonatum kingianum,17-22 parts of honeysuckle, 5-7 parts of sorbitol, 12-15 parts of chitosan, 2-6 parts of glycerin, 8-12 parts of maltodextrin and 23-40 parts of magnesium stearate. Through reasonable combination, proper sweet taste, color and luster and smell of the drug are kept, and the dendrobium lozenge has the effects of clearing away heat and toxic materials, resisting bacteria, diminishing inflammation, promoting the secretion of saliva or body fluid and smoothing the throat, and has a significant effect in treatment of sphagitis and oral ulcer; and according to the preparation method of the dendrobium lozenge, the effective components in the raw materials can be stored, and the preparation method is reasonable in production technology and suitable for industrial production.

Description

technical field [0001] The invention relates to the technical field of medicine processing, in particular to a dendrobium buccal tablet and a preparation method thereof. Background technique [0002] Buccal tablets refer to compressed tablets that dissolve slowly in the oral cavity, which can produce long-lasting medicinal effects on the oral cavity and pharynx. They are used for local anti-inflammatory, disinfection, swelling, and stimulation of mucous membrane secretion. drug. Buccal tablets are welcomed by patients because of their good taste and convenient way of taking. However, there are also the following problems in the buccal tablets of traditional Chinese medicine: 1. The compatibility of traditional Chinese medicine is unreasonable, and the drug effect is not good; Edible, overdose causes adverse reactions; 3. The preparation method is not refined enough to fully exert the drug effect. Contents of the invention [0003] Aiming at the deficiencies of the above...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61K9/20A61P11/04A61P1/02A61K31/045
CPCA61K9/0056A61K9/2059A61K31/045A61K36/355A61K36/8969A61K36/8984A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 李玉萍戴好富蔡彩虹
Owner 海南诗博丽生物科技有限公司