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Easy-to-absorb oral ulcer patch and preparation method thereof

An oral ulcer and easy-to-absorb technology, applied in the field of medical products, can solve the problems of slow effect and achieve the effect of fast onset, good mildness and high antibacterial activity

Active Publication Date: 2017-10-24
上海耀大生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, the oral ulcer patch of the above-mentioned patent also has certain deficiencies. After the patch is attached, the active ingredient of the drug cannot be fully absorbed by the oral mucosa, so the effect is slow

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] An easily absorbed oral ulcer patch, comprising the following components by weight:

[0038] Active ingredient microemulsion 25 parts,

[0039] 35 parts of propolis,

[0040] 15 pieces of borneol,

[0041] 3 parts antibacterial agent,

[0042] 5 parts lubricant,

[0043] 8 parts of sodium carboxymethylcellulose,

[0044] 4 parts of coating agent,

[0045] Appropriate amount of pH adjuster.

[0046] Wherein, the active ingredient microemulsion is a water-in-oil-in-water microemulsion containing traditional Chinese medicine extracts for treating oral ulcers and western medicines for treating oral ulcers. The preparation method is as follows: dissolving Chinese medicine extract and western medicine in water, adding a surfactant (sodium dodecylbenzene sulfonate) and stirring evenly to obtain an aqueous phase solution; adding the aqueous phase solution to the In the tea tree oil of surfactant (sodium dodecylbenzene sulfonate), water-in-oil granules are obtained after ...

Embodiment 2

[0055] An easily absorbed oral ulcer patch, comprising the following components by weight:

[0056] Active ingredient microemulsion 20 parts,

[0057] 30 parts of propolis,

[0058] 10 pieces of ice flakes,

[0059] antibacterial agent,

[0060] parts of lubricant,

[0061] 5 parts of sodium carboxymethylcellulose,

[0062] 2 parts of coating agent,

[0063] Appropriate amount of pH adjuster.

[0064] Wherein, the active ingredient microemulsion is a water-in-oil-in-water microemulsion containing traditional Chinese medicine extracts for treating oral ulcers and western medicines for treating oral ulcers. The preparation method is as follows: dissolving Chinese medicine extract and western medicine in water, adding a surfactant (ammonium lauryl sulfate) and stirring evenly to prepare an aqueous phase solution; adding the aqueous phase solution to the In the tea tree oil of activator (ammonium lauryl sulfate), the water-in-oil granule is made after fully stirring; ) in ...

Embodiment 3

[0072] An easily absorbed oral ulcer patch, comprising the following components by weight:

[0073] Active ingredient microemulsion 30 parts,

[0074] 40 parts of propolis,

[0075] 20 pieces of ice flakes,

[0076] Antibacterial agent 5 parts,

[0077] 6 parts lubricant,

[0078] 10 parts of sodium carboxymethylcellulose,

[0079] 6 parts of coating agent,

[0080] Appropriate amount of pH adjuster.

[0081] Wherein, the active ingredient microemulsion is a water-in-oil-in-water microemulsion containing traditional Chinese medicine extracts for treating oral ulcers and western medicines for treating oral ulcers. The preparation method is as follows: dissolving Chinese medicine extract and western medicine in water, adding a surfactant (sodium dodecylbenzene sulfonate) and stirring evenly to obtain an aqueous phase solution; adding the aqueous phase solution to the In the tea tree oil of surfactant (sodium dodecylbenzene sulfonate), water-in-oil granules are obtained af...

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Abstract

The invention relates to the field of medical products, and provides an easy-to-absorb oral ulcer patch and a preparation method thereof. The oral ulcer patch is prepared from the following components in parts by weight: 20-30 parts of active ingredient micro-emulsion particles, 30-40 parts of propolis, 10-20 parts of borneol, 1-5 parts of an antibacterial agent, 4-6 parts of a lubricant, 5-10 parts of sodium carboxymethylcellulose, 2-6 parts of a coating agent and 0-10 parts of a pH modifier. The oral ulcer patch contains the active ingredient micro-emulsion particles, wherein the active ingredient micro-emulsion particles contain medicinal ingredients and are easily absorbed by oral mucosa, thereby being fast in acting. In addition, the oral ulcer patch contains an antibacterial agent which is high in antibacterial activity and good in tenderness, and does not cause excessive damage to cells.

Description

technical field [0001] The invention relates to the field of medical products, in particular to an easily absorbable oral ulcer patch and a preparation method thereof. Background technique [0002] Oral ulcers occur in the ulcerative injury of the oral mucosa. When oral ulcers attack, the pain is severe, and the local burning pain is obvious. In severe cases, it will also affect eating and speaking, and have a great impact on daily life. There are many types of oral veneers on the market today. [0003] Patent CN200410060586.7 discloses a patch for oral ulcer, which is composed of two layers, a drug-containing adhesive layer and a waterproof protective layer. The weight ratio of each effective raw material drug in the drug adhesion layer is Qingdai: alum: borneol = 0.5-10: 0.5-10: 0.05-2; the ratio of the total amount of raw material drug to the total amount of adhesive material is 1: 2-8; The drug patch is convenient for application, quick in treatment and less in pain. S...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/534A61K36/539A61K36/355A61K36/258A61K36/9068A61K9/70A61K9/113A61K47/46A61K47/44A61P1/02A61P31/02A61K31/198A61K31/185A61K31/045A61K31/728A61K31/78
CPCA61K9/006A61K9/113A61K9/7007A61K31/045A61K31/185A61K31/198A61K31/728A61K31/78A61K36/258A61K36/355A61K36/534A61K36/539A61K36/9068A61K47/44A61K47/46A61K2300/00
Inventor 吴苗
Owner 上海耀大生物科技有限公司
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