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Photoacoustic sensing device and method of operation thereof

A technology of acoustic sensing and photoacoustic signals, applied in the field of decorrelation values ​​of blood glucose, blood core temperature, and blood oxygen saturation, which can solve problems such as poor specificity and changing dielectric properties

Active Publication Date: 2020-08-11
NANYANG TECH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Unfortunately, this method is less specific since many factors such as diseases affecting cell membranes can also significantly alter dielectric properties

Method used

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  • Photoacoustic sensing device and method of operation thereof
  • Photoacoustic sensing device and method of operation thereof
  • Photoacoustic sensing device and method of operation thereof

Examples

Experimental program
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Embodiment Construction

[0067] First go to figure 1 , An exemplary photoacoustic sensing device 100 for non-invasive measurement of blood parameters of a subject 102 is shown. The photoacoustic sensing device 100 includes a photoacoustic sensor 104, a first sensor processing module 112, a second sensor processing module 116, and a third sensor processing module 118. The photoacoustic sensing device 100 may optionally include the light source 108, or this may be provided separately.

[0068] The light source 108 (e.g., a laser, such as a laser diode) is configured to emit light 110 toward the subject 102 (or otherwise a target area of ​​the subject, such as image 3 , Figure 5 with Figure 8 Shown in more detail in). When the light 110 from the light source 108 illuminates the area of ​​the subject 102, the photoacoustic sensor 104 picks up the induced photoacoustic signal (for example, sound wave) 106. The photoacoustic sensor 104 outputs the sensed photoacoustic signal 114 for use by one or more of ...

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Abstract

A photoacoustic sensing device (100) for noninvasive measurement of a blood parameter of a subject (102) includes a photoacoustic signal for sensing a photoacoustic signal induced when a region of the subject is illuminated by a light source (108). (106) of the photoacoustic sensor (104). The first sensor processing module (112) may derive blood oxygen saturation using the sensed photoacoustic signal (114). The second sensor processing module (116) may use the sensed photoacoustic signal to derive the blood core temperature. A third sensor processing module (118) may use the sensed photoacoustic signal to derive blood glucose. The sensing device is configured to derive at least one of: a decorrelated value (120) of the subject's blood oxygen saturation; a decorrelated value (122) of the subject's blood core temperature; and a subject's blood glucose The decorrelation value of (124).

Description

Technical field [0001] The invention relates to a photoacoustic sensing device for non-invasive measurement of blood parameters of a subject. The present invention may also involve deriving a decorrelation value of the blood oxygen saturation of the subject. The invention may also involve deriving a decorrelation value of the blood core temperature of the subject. The invention may also involve deriving a decorrelation value of the subject's blood glucose. The invention also relates to a corresponding method. Background technique [0002] The photoacoustic (PA) effect refers to the sound wave generation of a material via a thermoelastic mechanism when illuminated by, for example, intensity modulated light. It is a fast-growing multi-wave technology, which is increasingly used in biomedical testing because of its high-resolution detection of rich optical contrast at depth (down to several centimeters) in the living body. Unique ability [1]. Since blood provides the main contr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/00A61B8/00
CPCA61B5/01A61B5/14532A61B5/14542A61B5/7278A61B5/0095A61B5/1477
Inventor 郑元谨封晓华高飞
Owner NANYANG TECH UNIV