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A sample receptacle, sample container and method of use

A receiver and sample technology, applied in chemical instruments and methods, biochemical equipment and methods, laboratory containers, etc., can solve the problems of bulky, expensive systems, and difficult to use small volumes of liquids

Pending Publication Date: 2017-12-01
MASTAPLEX LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Common methods of pipetting liquids can provide very precise liquid volumes, but require experience and skill to achieve consistent results and are time consuming
In addition, pipettes have a limited orifice diameter, which can make it difficult to pipette biological samples such as curd
[0004] Small capillaries can be used to transfer small volumes of liquids, but these small volumes are difficult to work with and do not allow simultaneous collection of large numbers of samples of constant and sufficient volume for typical laboratory processing
[0005] Some automated dispensing systems are available, but may be too expensive, complex, or cumbersome for small-scale analyses

Method used

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  • A sample receptacle, sample container and method of use
  • A sample receptacle, sample container and method of use
  • A sample receptacle, sample container and method of use

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0111] In this example, use Figure 1 to Figure 4 A receiver of the form shown was used to assess the change in volume of each chamber when the sample fluid was whole homogenized milk. The receiver has 3 rows A to C and 8 columns 1 to 8. A cylindrical vent hole with a diameter of 0.2 mm was provided in the base of each cavity. Five trials R1 to R5 show volume in ul in each chamber, mean volume in each chamber, standard deviation (Std) and coefficient of variation (CV) and finally Std and CV for all trials .

[0112] Pour at A8 (User 2)

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example 2

[0120] In this example, use Figure 1 to Figure 4 A receiver of the form shown was used to assess the change in volume of each chamber when the sample fluid was whole homogenized milk. The receiver has 3 rows A to C and 8 columns 1 to 8. A cylindrical vent hole with a diameter of 0.2 mm was provided in the base of each cavity. Five trials R1 to R5 show volume in ul in each chamber, mean volume in each chamber, standard deviation (Std) and coefficient of variation (CV) and finally Std and CV for all trials .

[0121] Pour at C8 (User 2)

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example 3

[0129] In this example, use Figure 1 to Figure 4 A receiver of the form shown was used to assess the change in volume of each chamber when the sample fluid was whole homogenized milk. The receiver has 3 rows A to C and 8 columns 1 to 8. A cylindrical vent hole with a diameter of 0.2 mm was provided in the base of each cavity. Five trials R1 to R5 show volume in ul in each chamber, mean volume in each chamber, standard deviation (Std) and coefficient of variation (CV) and finally Std and CV for all trials .

[0130] Pour at A1 (User 2)

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Abstract

The invention discloses a sample receptacle, a sample container and a method of use. The sample receptacle including one or more receptacle cavities each having an opening dimensioned such that a liquid within the cavity is retained when the cavity opening is oriented downwardly and / or a gas vent in the base of each cavity sized and positioned to allow gases contained within the cavity to egress whilst preventing the egress of liquid at atmospheric pressure. A sample liquid may be poured into the sample receptacle so that the level of the sample liquid is above each cavity opening and the sample receptacle inverted so as to remove liquid above each cavity whilst retaining sample liquid in each sample receptacle when inverted. This may be used for sample separation or to provide relatively uniform sample volumes to sample wells of a sample container when mated. In another embodiment plungers may be used to eject liquid from receptacle wells via an aperture in the base of each receptacle well.

Description

technical field [0001] The present invention relates to a sample receptacle for providing a desired volume of sample liquid. The sample receptacle can be used to provide a relatively constant volume of liquid sample to a wellbore of a microplate containing various concentrations of reactants for sample liquid analysis or some other application. Background technique [0002] In some fluid testing applications the analysis of large numbers of samples with consistent volumes is required, such as in multiplex assays, biological fluid analysis including, for example, antibiotic susceptibility testing using microdilution (for example for the isolation of bacteria from mastitis milk) and Chemical residue test. [0003] Several techniques are currently employed to deliver liquid samples of consistent volume for laboratory analysis. Common methods of pipetting liquids can provide very precise liquid volumes, but require experience and skill to achieve consistent results and are tim...

Claims

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Application Information

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IPC IPC(8): B01L3/00G01F11/26G01N1/20
CPCG01F11/262G01F13/00B01L3/50853B01L3/5635B01L2300/047B01L2300/048B01L2300/0829B01L2400/0457C12Q1/18B01L2400/0478G01N35/1009G01N35/1072G01N35/1074
Inventor 奥拉夫·博克
Owner MASTAPLEX LTD