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Oral liquid with cough relieving effect and preparation method thereof

An oral liquid and a technology of action are applied to the oral liquid with antitussive effect and the field of preparation thereof, which can solve the problems of side effects, poor treatment effect, destruction of elastic tissue of alveolar walls, etc. good treatment effect

Inactive Publication Date: 2017-12-15
温美群
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, long-lasting and severe cough can affect rest, and is easy to consume physical strength, and can cause damage to the elastic tissue of the alveolar wall, and induce emphysema.
[0004] At present, there are many types of medicines for treating cough, including pure Chinese medicine preparations, Western medicine preparations and Chinese and Western medicine mixtures. Western medicine preparations have quick effects, but have side effects and are prone to drug resistance. Pure Chinese medicine preparations and Chinese and Western medicine mixtures have unreasonable drug compatibility. , Defects with poor treatment effect

Method used

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  • Oral liquid with cough relieving effect and preparation method thereof
  • Oral liquid with cough relieving effect and preparation method thereof
  • Oral liquid with cough relieving effect and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] A cough-relieving oral liquid, the preparation method is as follows:

[0047] (1) Preparation of chicken gall extract

[0048] Weigh 200g of chicken gall, crush the chicken gall, press, filter the effluent, collect the bile, add 98vt% ethanol 6 times its volume to the bile, stir at room temperature, let it stand for 20h, filter and collect the filtrate, concentrate the filtrate and evaporate to dryness , collect ethanol to obtain chicken bile extract.

[0049] (2) Preparation of the first extract

[0050] Weigh 230g of Adenophora japonicus and 200g of Scutellaria baicalensis, add purified water 5 times the total weight of medicinal materials after mixing, heat to a slight boil and extract for 2.5h, and collect the filtrate by filtration. Then add pure water 4 times its weight to the medicinal materials, heat to a slight boil for extraction for 1.5 hours, and collect the filtrate by filtration. Combine the two filtrates, heat to boiling and concentrate until the relat...

Embodiment 2

[0059] A cough-relieving oral liquid, the preparation method is as follows:

[0060] (1) Preparation of chicken gall extract

[0061] Weigh 180g of chicken gall, crush the chicken gall, press, filter the effluent, collect the bile, add 98vt% ethanol 7 times its volume to the bile, stir at room temperature, let it stand for 18h, filter and collect the filtrate, concentrate the filtrate and evaporate to dryness , collect ethanol to obtain chicken bile extract.

[0062] (2) Preparation of the first extract

[0063]Weigh 250g of Adenophora japonicus and 180g of Scutellaria baicalensis, add pure water 6 times the total weight of medicinal materials after mixing, heat to a slight boil and extract for 2.5h, and collect the filtrate by filtration. Then add pure water 3 times its weight to the medicinal materials, heat to a slight boil for extraction for 1.5 hours, and collect the filtrate by filtration. Combine the two filtrates, heat to boiling and concentrate until the relative d...

Embodiment 3

[0072] A cough-relieving oral liquid, the preparation method is as follows:

[0073] (1) Preparation of chicken gall extract

[0074] Weigh 220g of chicken gall, crush the chicken gall, press, filter the effluent, collect the bile, add 5 times its volume of 98vt% ethanol to the bile, stir at room temperature, let it stand for 24h, filter and collect the filtrate, concentrate the filtrate and evaporate to dryness , collect ethanol to obtain chicken bile extract.

[0075] (2) Preparation of the first extract

[0076] Weigh 200g of Adenophora japonicus and 220g of Scutellaria baicalensis, add pure water 4 times the total weight of medicinal materials after mixing, heat to a slight boil for extraction for 2 hours, and collect the filtrate by filtration. Then add 5 times the weight of pure water to the medicinal materials, heat to a slight boil for extraction for 2 hours, and collect the filtrate by filtration. Combine the two filtrates, heat to boiling and concentrate until the...

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Abstract

The invention discloses oral liquid with a cough relieving effect. The oral liquid is prepared from the following raw materials: 200 to 250g of radix glehniae, 180 to 220g of radix scutellariae chinensis, 180 to 220g of chicken gall, 150 to 180g of semen ziziphi spinosae, 150 to 180g of semen boitae, 50 to 70g of sucrose and pure water for reaching the constant volume of 1000ml. The invention also provides a preparation method of the oral liquid. The oral liquid uses medicinal materials such as the radix glehniae, the radix scutellariae chinensis and the chicken gall extracts with the cough relieving effect as major ingredients; the semen ziziphi spinosae and the semen boitae with the nerve calming effect are added, so that the medicine effect is favorably exerted. The oral liquid has the advantages of fast effect taking and good treatment effect on cough caused by upper respiratory infection.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to an oral liquid with antitussive effect and a preparation method thereof. Background technique [0002] Coughing is a protective respiratory reflex action for the human body to clear secretions or foreign objects in the respiratory tract. It is the main symptom of respiratory diseases, such as dry cough without sputum or very little sputum, which is common in the early stage of acute pharyngitis and bronchitis; acute cough that occurs suddenly is more common in bronchial foreign bodies; long-term chronic cough is more common in chronic Bronchitis, tuberculosis, etc. [0003] The unfavorable effect of coughing is that it can spread the tracheal lesions to the adjacent small bronchi, aggravating the condition. In addition, long-lasting and severe cough can affect rest, and is easy to consume physical strength, and can cause damage to the elastic tissue of the alveola...

Claims

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Application Information

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IPC IPC(8): A61K36/725A61K9/08A61P11/14A61K35/57
CPCA61K9/0095A61K35/57A61K36/14A61K36/23A61K36/539A61K36/725A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 温美群
Owner 温美群