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Medicinal composition for treating gout

A composition and drug technology, applied in the field of pharmaceutical composition for the treatment of gout, to enhance the therapeutic effect and reduce the effect of inflammatory factors

Active Publication Date: 2017-12-15
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Lycium barbarum is widely used as a common edible berry or health food. However, there is no research report on the use of Lycium barbarum or its extracts for the treatment of gout. Reports on Combined Use of Narcisine

Method used

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  • Medicinal composition for treating gout
  • Medicinal composition for treating gout

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Example 1 Pharmaceutical composition of the present invention

[0049] Take colchicine and Lycium nigra ethanol extract at 0.1:200, add an appropriate amount of filler to prepare granules, tablets, powders and pills.

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Abstract

The invention provides a medicinal composition for treating gout. The medicinal composition comprises colchicines and black lycium barbarum or an extract of black lycium barbarum. Studies show that a black lycium barbarum ethanol extract is capable of effectively treating gout and reducing inflammation factors, in addition, with the combination of the black lycium barbarum and the colchicines, the treatment effects of the two components on gout can be remarkably improved, and a relatively good option is provided for clinical medication.

Description

technical field [0001] The present invention relates to a pharmaceutical composition for treating gout. Background technique [0002] Gout is a group of heterogeneous diseases caused by long-term purine metabolism disorder and increased blood uric acid causing tissue damage. The clinical features are hyperuricemia (HUA), recurrent gouty acute arthritis, tophi deposition, characteristic chronic arthritis and joint deformities, often involving the kidneys, causing chronic interstitial nephritis and renal uric acid stone formation. The biochemical hallmark of gout is hyperuricemia, which refers to the supersaturation of urate in the extracellular fluid. Urate (monosodium uratecrystal, MSU) is deposited in the form of crystals in the joints and tissues around the joints to cause a series of acute inflammatory reactions, that is, gout. It is generally believed that blood uric acid ≥ 416 μmol / L is hyperuricemia, and about 5%-12% of patients with hyperuricemia will develop gout, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P19/06A61P29/00A23L33/105A61K31/165
CPCA61K31/165A61K36/815A61K2236/333A23L33/105A61K2300/00
Inventor 索有瑞张弓王洪伦
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST