Unlock instant, AI-driven research and patent intelligence for your innovation.

A pharmaceutical composition for treating gestational hypertension complicated with preeclampsia

A technology for pregnancy-induced hypertension and preeclampsia, applied in the field of medicine, can solve the problems of slow onset, blood pressure control, unfavorable patients, etc., and achieve the effect of improving blood pressure reduction, reducing urine protein, and avoiding adverse reactions

Inactive Publication Date: 2018-05-15
刘玉莹
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, the prescription of the above-mentioned traditional Chinese medicine compound is relatively large, often requires precious medicinal materials such as antelope and bezoar, and the onset of oral administration is slow, which is not conducive to the timely control of blood pressure of patients

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A pharmaceutical composition for treating gestational hypertension complicated with preeclampsia
  • A pharmaceutical composition for treating gestational hypertension complicated with preeclampsia
  • A pharmaceutical composition for treating gestational hypertension complicated with preeclampsia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1 Oral solution for treating pregnancy-induced hypertension complicated with preeclampsia and its preparation process

[0042] The following is the composition and preparation process of the oral liquid for treating gestational hypertension complicated with preeclampsia.

[0043] 1. Drug prescription

[0044]

[0045] Second, the preparation process:

[0046] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornus, Moutan cortex, Chinese yam, Poria cocos, Alisma, and Leiwan, and pulverize them separately, pass through a 40-mesh sieve, and mix to obtain medicinal powder;

[0047] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and decoct for 2 hours, Combine the water decoction and let it cool down;

[0048] (3...

Embodiment 2

[0051] Example 2 Oral granules for treating gestational hypertension complicated with preeclampsia and its preparation process

[0052] The following are the prescription and preparation process of oral granules for treating pregnancy-induced hypertension complicated with preeclampsia.

[0053] 1. Drug prescription

[0054]

[0055] Second, the preparation process:

[0056] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornus, Moutan cortex, Chinese yam, Poria cocos, Alisma, and Leiwan, and pulverize them separately, pass through a 40-mesh sieve, and mix to obtain medicinal powder;

[0057] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and decoct for 2 hours, Combine the water decoction and let it cool down;

[0058] (3...

Embodiment 3

[0061] Embodiment 3 Pharmacodynamics study in vivo

[0062] 1. Drugs and their preparation

[0063] 1. Experimental drug: the clear ointment of prescription 1-3 in the embodiment 1 is selected for the experimental drug.

[0064] Comparing drugs:

[0065] Comparative drug 1 and comparative drug 2 were prepared respectively according to the following prescriptions.

[0066]

[0067] The preparation process of contrast drug 1 is as follows:

[0068] (1) Pulverization: Take the prescription amount of medlar, chrysanthemum, Rehmannia glutinosa, wine cornel, Moutan cortex, Chinese yam, Poria cocos, and Alisma chinensis, respectively pulverize, pass through a 40-mesh sieve, and mix to obtain medicinal material powder;

[0069] (2) Extraction: add water to the powder obtained in step (1) and decoct twice, add water 6 times the weight of the medicinal powder for the first time and decoct for 6 hours, add water 4 times the weight of the medicinal powder for the second time and dec...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating gestational hypertension complicated with preeclampsia. The medicinal composition is prepared by extracting medlar, chrysanthemum, rehmannia glutinosa, wine cornus, cortex moutan, yam, poria cocos, alisma and thunder pill by decocting in water and precipitating with alcohol. Its formulation is preferably an oral liquid formulation. The composition can significantly reduce the blood pressure and urine protein of rats with pregnancy-induced hypertension complicated with preeclampsia, thereby alleviating the symptoms of pregnancy-induced hypertension and preventing the occurrence of eclampsia.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating gestational hypertension complicated with preeclampsia. Background technique [0002] Gestational hypertension is a disease unique to pregnant women, that is, high blood pressure that occurs after 20 weeks of pregnancy. The incidence rate in my country is 9.4%, and the incidence rate reported abroad is about 7% to 12%. The deterioration of the disease will be accompanied by eclampsia, severe convulsions, affecting the health and safety of mothers and infants, and is one of the main causes of maternal and perinatal morbidity and death. [0003] At present, the pathogenesis of pregnancy-induced hypertension is still unclear. Western medicine mainly uses symptomatic treatment for pregnancy-induced hypertension, that is, the use of antihypertensive drugs to relieve symptoms (Guidelines for the diagnosis and treatment of hypertensive disor...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P15/00A61P9/12
Inventor 刘玉莹谭志军寇晨光高继友
Owner 刘玉莹