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A kind of medicine for treating tinnitus and its application

A technology of medicine and raw materials, applied in the field of medicine for treating tinnitus and its preparation

Inactive Publication Date: 2020-06-05
武汉市第三医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the most widely studied is the influence of 5-HT1A receptors on the auditory pathway, while 5-HT1B and 2C are rarely mentioned.

Method used

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  • A kind of medicine for treating tinnitus and its application
  • A kind of medicine for treating tinnitus and its application
  • A kind of medicine for treating tinnitus and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The medicine for treating tinnitus of the present invention is composed of the following raw materials in parts by weight: Rehmannia glutinosa 10, Cornus officinalis 20, Mulberry fruit 10, Cuscuta 20, Curcuma 10, Polygala 10, Alisma 10, Shichangpu 20, Pueraria 10, Salvia 15 , Panax notoginseng 10, magnet 40, vitex 5, cicada slough 10.

Embodiment 2

[0024] The medicine for treating tinnitus of the present invention is composed of the following raw materials in parts by weight: Rehmannia glutinosa 20, Cornus officinalis 10, Mulberry fruit 20, Cuscuta 10, Curcuma 20, Polygala 6, Alisma 15, Shichangpu 10, Pueraria 20, Salvia 6 , Panax notoginseng 20, magnet 20, vitex 15, cicada slough 6.

Embodiment 3

[0026] The medicine for treating tinnitus of the present invention is composed of the following raw materials in parts by weight: Rehmannia glutinosa 15, Cornus officinalis 12, Mulberry fruit 12, Cuscuta 12, Curcuma 15, Polygala 6, Alisma 10, Shichangpu 12, Pueraria 12, Salvia miltiorrhiza 10 , notoginseng 12, magnet 30, vitex 10, cicada slough 6.

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PUM

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Abstract

The invention discloses medicine for treating tinnitus as well as a preparation method and a purpose thereof. The medicine is prepared from the following raw materials in parts by weight: 10 to 20 parts of prepared rehmannia roots, 10 to 20 parts of fructus corni, 10 to 20 parts of mulberry fruits, 10 to 20 parts of seeds of Chinese dodder, 10 to 20 parts of radix curcumae, 1 to 10 parts of radixpolygalae, 5 to 15 parts of rhizoma alismatis, 10 to 20 parts of rhizoma acori tatarinowii, 10 to 20 parts of radix puerariae, 5 to 15 parts of radix salviae miltiorrhizae, 10 to 20 parts of radix notoginseng, 20 to 40 parts of magnetite, 5 to 15 parts of fructus viticis and 1 to 10 parts of cicada slough. The 5-HT1B expression in tinnitus rat SGN is increased; the 5-HT2C is reduced. The allopathic effect can be generated, so that the auditory system inhibition and excitement states are balanced; the tinnitus as the subjective sound is weakened or disappears; the condition can become the experiment basis for relieving the tinnitus.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for treating tinnitus and its preparation method and application. Background technique [0002] With the rapid development of modern society and the increasing living environment and mental pressure, tinnitus, deafness, and vertigo are called the three major symptoms of otology that urgently need to be solved. In particular, tinnitus, as a subjective symptom, gradually leads to irritability, anxiety, and depression, and anxiety can make patients more sensitive to tinnitus, thus causing a vicious circle. The treatment of tinnitus is imminent, and the abnormal release of certain neurotransmitters causes neurospontaneous neuropathy. The discharge activity, which is misinterpreted as a sound by the auditory center, that is, tinnitus has become the focus of research. Glutamate is the most important excitatory amino acid in the mammalian brain, and NMD...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P27/16A61K33/26A61K35/64
CPCA61K33/26A61K35/63A61K36/258A61K36/39A61K36/40A61K36/43A61K36/488A61K36/537A61K36/605A61K36/69A61K36/804A61K36/85A61K36/884A61K36/888A61K36/9066A61K2300/00
Inventor 孙勤国江波吕琨罗蒙郭乃燕徐鸿婕杨倩
Owner 武汉市第三医院