Method and system for controlling six-way valve of ultra performance liquid chromatograph

Abstract

The invention provides a method and system for controlling a six-way valve of an ultra performance liquid chromatograph, and relates to the technical field of ultra performance liquid chromatographs.The method for controlling the six-way valve of the ultra performance liquid chromatograph comprises that a central processing circuit determines a corresponding encoder code value according to a target position to which the six-way valve is rotated; a command for starting the six-way valve to rotate is sent to an FPGA processing circuit; the FPGA processing circuit outputs a PWM wave in order tocontrol a motor drive circuit to drive a stepping motor, and therefore a four-way optoelectronic switch generates a state change; the state value of the four-way optoelectronic switch which generatesthe state change is detected, and the state value is compared with the encoder code value; when the state value is equal to the encoder code value, it is determined that the six-way valve is rotated to the target position, and the flag bit of six-way valve rotation completion is set as a true value; when the central processing circuit reads that the flag bit of six-way valve rotation completion isthe true value, and a six-way valve rotation stop command is sent to the FPGA processing circuit to stop rotation of the six-way valve. According to the invention, the fluid path switching accuracy and safety can be improved.

Description

technical field [0001] The invention relates to the technical field of ultra-high performance liquid chromatography, in particular to a method and system for controlling a six-way valve of an ultra-high performance liquid chromatography. Background technique [0002] Ultra Performance Liquid Chromatography (Ultra Performance Liquid Chromatography, UPLC) is an important application of chromatography, which uses liquid as the mobile phase, and uses an ultra-high pressure infusion system, such as an ultra-high pressure infusion pump, to combine a single solvent with different polarities or Different proportions of mixed solvents, buffers, etc. are flow-connected, and pumped into a chromatographic column equipped with a stationary phase with the sample to be tested. After the components of the sample to be tested are separated in the column, they enter the detector for detection, thereby realizing qualitative and quantitative analysis. Ultra-high performance liquid chromatograp...

AI Technical Summary

Problems solved by technology

[0004] Embodiments of the present invention provide a method and system for controlling a six-way valve of an ultra-high performance liquid chromatograph, so as to solve the problem of manual operation to switch the six-way valve in the current high-pressure liquid circuit of an ultra-high performance liquid chromatograph. Precise liquid circuit switching cannot be completed, and manual operation is likely to cause dangerous problems such as liquid leakage and pressure instability

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