Automatic stem cell culture system

Abstract

The invention discloses an automatic stem cell culture system which comprises a grabbing mechanism, a guide rail mechanism, a feed bin, a centrifuge, an incubator, a liquid distribution center, a discharge bin and an air purifying system, wherein the feed bin is used for feeding consumable material for single culture of stem cells; the grabbing mechanism is used for grabbing and placing a cultureflask; the guide rail mechanism is used for driving the grabbing mechanism to move; the centrifuge is used for centrifuging the stem cells in the culture flask; the incubator is used for culturing thestem cells to obtain a finished product of stem cells; the liquid distribution center is used for inoculating an empty culture flask with seed stem cells in the culture flask in the feed bin, and concentrating all finished products of stem cells to be collected when single batch is finished and sub-packaging in freezing tubes; the discharge bin is used for transferring out the freezing tubes containing the finished products of stem cells; the air purifying system is used for purifying air of internal environment for the stem cell culture. The system disclosed by the invention can realize automation of stem cell culture and improve the culture efficiency.

Description

technical field [0001] The invention relates to the technical field of cell preparation, in particular to an automatic stem cell culture system. Background technique [0002] The 21st century is the era of cell therapy. Whether it is the "tumor cell immunotherapy" represented by CAR-T or the "stem cell therapy" of Nobel Prize-winning universal cells, they all have a market space of hundreds of billions of dollars and lead the future medical revolution. Cell therapy has become the fourth largest medical method after protein drugs, chemical drugs, and medical devices. Stem cell therapy is a direction of cell therapy, and stem cell culture technology is the foundation of stem cell therapy. The traditional way of manually culturing stem cells has disadvantages such as low efficiency, high infection probability, high error rate, and difficult quality control. Due to the different experience, techniques and habits of operators, the state of the stem cells cultured is often inconsi...

AI Technical Summary

Problems solved by technology

[0003] The existing automated cell culture system is difficult to scale up, unable to realize the automation and intelligence of the whole process, and still requires a lot of manual participation; manual recording of production data makes it difficult to realize the comprehensive utilization of production big data; most of them are dedicated cell equipment, and transplantation between different cell processes Poor adaptability; the environmental requirements are still high, the risk of artificial pollution still exists, and the preparation and application are difficult to register and authenticate to form large-scale replication and promotion

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