Pharmaceutical composition containing decoquinate and application of pharmaceutical composition
A technology containing decoquinate and decoquinate, which is applied in the field of pharmaceutical compositions containing decoquinate, can solve the problems of reduced therapeutic effect of antibacterial drugs, and achieve low production cost, low drug resistance and high therapeutic effect Good results
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[0018] Example 1
[0019] First, weigh the following raw materials according to the mass: 0.2kg of decoquinate, 0.12kg of mountain bean root, 0.1kg of stearic acid, 0.03kg of n-butanol, 0.07kg of aminobenzoic acid, and 0.05kg of isopropyl myristate; Surfactant stearic acid, co-surfactant n-butanol, co-solvent aminobenzoic acid and isopropyl myristate were stirred and mixed evenly with a glass rod, and then added decoquinate and shandougen in sequence, and then used a mixer After stirring and mixing uniformly, add 0.48kg of deionized water and put it in an ultrasonic cleaner with a power of 120W and ultrasonic for 5 hours until a uniform and transparent solution is formed; finally, it is moved into a vacuum drying oven at 55°C and dried for 4.5 hours to obtain a decoquine Pharmaceutical composition.
Example Embodiment
[0020] Example 2
[0021] First, weigh the following raw materials according to the mass: 0.23 kg of decoquinate, 0.17 kg of lecithin 0.13 kg of mountain bean root, 0.06 kg of n-pentanol, 0.1 kg of acetamide, and 0.08 kg of jojoba oil; then the surfactant lecithin, Co-surfactant n-pentanol, co-solvent acetamide and jojoba oil were stirred and mixed uniformly with a glass rod, then decoquinate and shandougen were added in sequence, and then mixed with a mixer, and then 0.8kg deionized water was added Put it into an ultrasonic cleaner with a power of 140W and sonicate it for 6 hours until a uniform and transparent solution is formed; finally, it is moved into a 60°C vacuum drying oven and dried for 5 hours to obtain a pharmaceutical composition containing decoquinate.
Example Embodiment
[0022] Example 3
[0023] First, weigh the following raw materials according to the mass: 0.28kg of decoquinate, 0.22kg of mountain pea root, 0.16kg of Tween-20, 0.08kg of isopropanol, 0.13kg of sodium salicylate, and 0.09kg of isopropyl myristate; Then the surfactant Tween-20, the co-surfactant isopropanol, the co-solvent sodium salicylate and the oil isopropyl myristate are stirred and mixed uniformly with a glass rod, and then the decoquinate and shandougen are sequentially added , And then use a mixer to mix evenly, add 1.0kg deionized water and put it in a 160W ultrasonic cleaner, ultrasonic for 7 hours, until a uniform and transparent solution is formed; finally, it is moved into a 70 ℃ vacuum drying oven and dried for 6 hours. Pharmaceutical composition of quinoate.
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