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Hand washing solution and preparation method thereof

A technology of hand sanitizer and raw materials, applied in the field of daily chemicals, can solve the problems of poor sterilization effect and obvious bacteriostatic effect, and achieve the effect of significant killing and inhibition effect, obvious effect and simple formula.

Inactive Publication Date: 2018-08-28
HANYI BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] An object of the present invention is to provide a kind of hand sanitizer, which can solve the problem that the existing hand sanitizers with plant extracts as the main antibacterial component only have obvious antibacterial effect and poor bactericidal effect, not only for Staphylococcus aureus, Escherichia coli , Candida albicans, Pseudomonas aeruginosa, etc. all have significant killing and inhibiting effects, and are mild and non-irritating to the skin, and have obvious moisturizing and skin care effects

Method used

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  • Hand washing solution and preparation method thereof
  • Hand washing solution and preparation method thereof
  • Hand washing solution and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] The preparation of embodiment 1 hemp extract

[0046] (1) Wash and air-dry the raw material cannabis stalks, cannabis flowers, cannabis leaves and / or cannabis roots;

[0047] (2) pulverize the above-mentioned air-dried raw materials to 10-40 mesh;

[0048] (3) Extract the obtained powder by cold soaking with 4-8 times the amount of 30%-60% ethanol for 1-3 times, each time for 0.5-2 hours;

[0049] (4) Combine the extracts and decolorize through 0.1-1wt% activated carbon adsorption;

[0050] (5) Concentrate under reduced pressure to a relative density of 1.01-1.03 at a temperature of 70°C;

[0051] Cannabis extract extracts are obtained, such as cannabis stalk core extract, cannabis flower extract, cannabis leaf extract, or a combination of two or three of them.

Embodiment 2

[0052] The preparation of embodiment 2 hemp extract

[0053] (1) using about 8-10 times the weight of the extraction solvent or its mixture to heat and reflux the stalk core, flowers, leaves and / or roots of cannabis for at least 1 hour;

[0054] (2) remove residue by filtration, and remove solvent under vacuum condition;

[0055] (3) heating the obtained extract at a temperature of about 110-135° C. for about 40 minutes;

[0056] (4) followed by chromatographic separation.

[0057] Described extraction solvent can be low-molecular-weight alcohol (such as methanol, ethanol, butanol or propanol); Acetate (such as methyl acetate or ethyl acetate); Ketone (such as acetone); Ether (such as methyl ether or ether) ; Low boiling aliphatic or aromatic hydrocarbons or chlorinated hydrocarbons.

[0058] In the chromatographic separation, the mobile phase mixture used in the chromatography is composed of methanol / water and acetic acid or ethanol / water and acetic acid.

Embodiment 3

[0059] The preparation of embodiment 3 hemp extract

[0060] (1) Using about 3-10 times the weight of the extraction solvent or its mixture to heat and reflux the stalk core, flowers, leaves and / or roots of cannabis for at least 1 hour;

[0061] (2) filter to remove residue;

[0062] (3) extracting at least twice with 1%-10% aqueous sodium hydroxide solution containing about 20wt% ethanol;

[0063] (4) The extract is mixed with 5% sulfuric acid solution so that the pH value is about 2-4;

[0064] (5) Then use a low-boiling point solvent (such as low-boiling point aliphatic hydrocarbons, aromatic hydrocarbons, chlorinated hydrocarbons, methyl acetate, ethyl acetate or mixtures thereof) to extract at least twice, and remove the solvent under low-temperature vacuum;

[0065] (6) followed by chromatographic separation.

[0066] Described extraction solvent can be low-molecular-weight alcohol (such as methanol, ethanol, butanol or propanol); Acetate (such as methyl acetate or et...

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Abstract

The invention provides a hand washing solution and a preparation method thereof, wherein the raw materials comprise, by weight, 25-75% of deionized water, 0.1-1% of a thickener, 0.1-30% of a Cannabissativa L extract, and 0.1-70% of an alcohol solvent. According to the present invention, the Cannabis sativa L extract is used as the main antibacterial and skin care ingredient, the formula is simple, the operation is easy, the hand washing solution integrating the functions of significant sterilization and skin care is prepared only from the one plant component, and the obtained product can significantly kill and inhibit Staphylococcus aureus, Escherichia coli, Candida albicans, Pseudomonas aeruginosa and the like, and has characteristics of mild property, no irritation to the skin, and obvious moisturizing and skin care effects.

Description

technical field [0001] The invention belongs to the field of daily chemicals and relates to an antibacterial cleaning product, in particular to a hand sanitizer and a preparation method thereof. Background technique [0002] As a daily chemical product for cleaning the skin of hands, hand sanitizer overcomes the problems that soap is easy to slip when used, difficult to store after use, naturally consumed, and easily contaminated with bacteria left by others after use to form secondary pollution. Occasions have gradually replaced soap. Hand sanitizer usually does not contain the alkaline ingredients in traditional soaps, and is relatively mild, so it is less irritating to the skin than soaps, but its decontamination ability is correspondingly lower than that of soaps. Most of them can only remove surface stains, sterilize and inhibit Bacteria are less effective. In order to solve the antibacterial problem of hand sanitizer, it is most common to add ingredients that can kil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/10A61Q19/00A61Q17/00
CPCA61K8/97A61Q17/005A61Q19/00A61Q19/10
Inventor 张可谭昕胡婷婷
Owner HANYI BIO TECH CO LTD