Supercharge Your Innovation With Domain-Expert AI Agents!

A traditional Chinese medicine composition for treating acute ischemic stroke

A technology for ischemic stroke and composition, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of limited treatment plan and low proportion of patients

Active Publication Date: 2020-10-27
东莞市中医院
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the first-choice effective treatment for acute stroke at home and abroad is to use alteplase for intravenous thrombolysis. There are many restrictions, because choosing this way to treat acute cerebral apoplexy has strict indications, contraindications and time windows. Therefore, the proportion of patients actually treated with intravenous thrombolysis is very low, as low as 1.23% in my country

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A traditional Chinese medicine composition for treating acute ischemic stroke
  • A traditional Chinese medicine composition for treating acute ischemic stroke
  • A traditional Chinese medicine composition for treating acute ischemic stroke

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0207] Embodiment 1 (granule)

[0208] Prescription: Take 100g of rhubarb, 100g of Fangfeng, 250g of gardenia, 15g of artificial bezoar, 100g of Tianzhuhuang, 100g of Magnolia officinalis, 100g of red peony root, 150g of Polygonum cuspidatum, totaling 915g.

[0209] Preparation method: first crush the artificial bezoar into fine powder, sieve, and set aside. Then extract the rest of Qiwei Yao with water heat and reflux for 4 hours, filter, collect the filtrate, concentrate the filtrate under reduced pressure to a relative density of 1.0-1.2 extract at 60°C, then place it in an oven and dry it under vacuum at 75°C to form a dry paste, crush it into fine powder. Finally, mix the obtained artificial bezoar fine powder and dry paste fine powder, then add appropriate amount of dextrin and starch to 450g, add water to make granules, then dry, granulate, and pack into 15g / bag.

Embodiment 2

[0210] Embodiment 2 (granule)

[0211] Prescription: Take 103g rhubarb, 100g Fangfeng, 240g gardenia, 15g artificial bezoar, 96g Tianzhuhuang, 100g Magnolia officinalis, 103g red peony root, 158g knotweed, 915g in total.

[0212] Preparation method: first crush the artificial bezoar into fine powder, sieve, and set aside. Then extract the rest of Qiwei Yao with water heat and reflux for 4 hours, filter, collect the filtrate, concentrate the filtrate under reduced pressure to a relative density of 1.0-1.2 extract at 60°C, then place it in an oven and dry it under vacuum at 75°C to form a dry paste, crush it into fine powder. Finally, mix the obtained artificial bezoar fine powder and dry paste fine powder, then add appropriate amount of dextrin and starch to 450g, add water to make granules, then dry, granulate, and pack into 15g / bag.

Embodiment 3

[0213] Embodiment 3 (granule)

[0214] Prescription: Take 102g rhubarb, 102g Fangfeng, 262g gardenia, 16g artificial bezoar, 100g Tianzhuhuang, 95g Magnolia officinalis, 95g red peony root, 143g knotweed, 915g in total.

[0215] Preparation method: first crush the artificial bezoar into fine powder, sieve, and set aside. Then extract the rest of Qiwei Yao with water heat and reflux for 4 hours, filter, collect the filtrate, concentrate the filtrate under reduced pressure to a relative density of 1.0-1.2 extract at 60°C, then place it in an oven and dry it under vacuum at 75°C to form a dry paste, crush it into fine powder. Finally, mix the obtained artificial bezoar fine powder and dry paste fine powder, then add appropriate amount of dextrin and starch to 450g, add water to make granules, then dry, granulate, and pack into 15g / bag.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a traditional Chinese medicine composition for treating acute ischemic stroke. The traditional Chinese medicine composition is prepared from an effective component and a medically acceptable excipient, wherein the effective component is prepared from the following crude drugs in percentage by weight: 10.4 to 11.5 percent of radix et rhizoma rhei, 10.4 to 11.5 percent of radix saposhnikoviae, 26.0 to 28.7 percent of fructus gardeniae, 1.6 to 1.7 percent of calculus bovis factitious, 10.4 to 11.5 percent of concretio silicea bambusae, 10.4 to 11.5 percent of cortex magnoliae officinalis, 10.4 to 11.5 percent of red paeony root and 15.6 to 17.2 percent of rhizoma polygoni cuspidati. The traditional Chinese medicine composition provided by the invention can be tablets,granules or capsules. A clinic research shows that the traditional Chinese medicine composition has a remarkable curative effect of treating the acute ischemic stroke.

Description

technical field [0001] The present invention relates to medicinal preparations, in particular to undetermined pharmaceutical preparations from medicinal plants. Background technique [0002] Acute ischemic stroke is a clinically common and high-incidence cerebrovascular disease, which has the characteristics of acute onset, rapid progress, high morbidity and mortality, and is recognized by the medical community as the number one killer of human health. One of the major threats to the health of urban and rural residents. With the continuous improvement of treatment methods, the mortality rate of stroke has decreased compared with before, but the disability rate has gradually increased. Traditional Chinese medicine believes that the triple energizer is related to the brain and brain, and the congestion of the triple energizer plays an important role in the pathological evolution of stroke. Clinically, the treatment of acute ischemic stroke by dredging and dredging the triple ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P9/10A61K35/413
CPCA61K35/413A61K36/238A61K36/575A61K36/65A61K36/704A61K36/708A61K36/71A61K36/744A61K36/899A61K2236/331A61K2236/51A61P9/10A61K2300/00
Inventor 宁为民杨康强陈敬毅谭静缪晓路
Owner 东莞市中医院
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com