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Improvements in and relating to instruments for processing cells

A device and cell technology, applied in the field of devices that process cells, can solve the problems of insufficient system quality and quantity output for therapeutic applications, etc.

Active Publication Date: 2018-10-23
GLOBAL LIFE SCI SOLUTIONS USA LLC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although various methods and systems for harvesting cells are known in the art, the quality and quantitative output of these systems is insufficient for therapeutic applications

Method used

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  • Improvements in and relating to instruments for processing cells
  • Improvements in and relating to instruments for processing cells
  • Improvements in and relating to instruments for processing cells

Examples

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Embodiment Construction

[0021] In order to more clearly and concisely describe and refer to the claimed subject matter of the invention, the following definitions are provided for certain terms, which are used in the following description and appended claims. Throughout the specification, the use of specific language should be considered as non-limiting examples.

[0022] refer to figure 1 , shows a cell harvesting device 10 which, in use, functions to absorb a liquid comprising suspended cells or similar microbial material, with the aim of largely separating the cells from the liquid or reducing the liquid content of the suspension. The device is operable to wash the cells etc. one or more times to remove unwanted material from the isolated cells. A preferred mechanism of function can be found in US2013 / 0029411.

[0023] The instrument 10 includes a housing 12 having a touch screen 14 and a door 16, shown closed and shown in dashed lines in an open position 16'. Door 16 allows insertion and remov...

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PUM

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Abstract

The present invention discloses an instrument suitable for processing cells for example culturing, concentrating or washing said cells, the instrument comprising: a housing for accommodating mechanical elements including at least one fluid pump; and a disposable processing kit complementary to the mechanical elements within the housing and comprising a fluid circuit including a fluid reservoir andplural fluid paths capable of carrying fluid flow caused by said pump(s), the instrument further including a mechanism for determining the quantity, or change in quantity of the fluid in the reservoir resulting from said fluid flow, the instrument yet further comprising a controller operable to control at least the pump and operable to perform a fault determination process, which includes the steps of determining the expected flow rate of said pump(s) calculated from the speed of the pump(s) and comparing that expected flow with the change in quantity of the fluid in the reservoir as determined by said mechanism.

Description

technical field [0001] The present invention relates to devices for treating cells, improved function of such devices, and improvements in their components. As used herein, "apparatus for processing cells" includes apparatus for harvesting cells, culturing cells, washing cells, separating cells, extracting cell products, etc., and the term "cells" includes cellular components and molecules derived from cells, such as antibodies and other proteins. Background technique [0002] For different therapeutic applications, such as cell therapy or tissue engineering, cells need to be efficiently processed, such as harvested from various sources. Examples of therapeutic applications include, but are not limited to, autologous or allogeneic transplantation of stem cells, transplantation of mature functional cells, T cells, modified human cells comprising T cells, or xenotransplantation of non-human cells. This application promotes the healing of damaged tissues or organs by regenera...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00B01L3/00C12M1/34C12M1/36A61M1/02
CPCC12M23/00C12M23/28C12M23/40C12M29/00C12M41/00C12M41/44C12M47/02C12M41/48C12M29/14C12M47/12
Inventor W.B.格里芬M.R.蒂明斯D.哈里斯S.洛维特J.道林D.奥苏利万
Owner GLOBAL LIFE SCI SOLUTIONS USA LLC
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