An isolated heart perfusion device suitable for rats
A perfusion and in vitro technology, used in material inspection products, biological tests, etc., can solve the problems of inaccurate position of perfusion needle inserted into the aorta, unstable heart fixation, etc., so as to reduce the time for adjusting the position of the perfusion needle and reduce fixation. Time, convenient operation effect
Active Publication Date: 2019-08-30
XINXIANG MEDICAL UNIV
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Problems solved by technology
[0004] In view of the above situation, in order to make up for the technical deficiencies existing in the prior art, the purpose of the present invention is to provide an isolated heart perfusion device suitable for rats, which effectively solves the problems of the heart being not firmly fixed and the perfusion needles in the existing perfusion device. Inaccurate insertion into the aorta
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[0018] The specific implementation manners of the present invention will be described in further detail below in conjunction with the accompanying drawings.
[0019] Depend on Figure 1 to Figure 9 Provide, the present invention comprises frame body 1, frame body 1 front is fixed with fixed rod 4, is hinged with movable rod 3 on fixed rod 4, does not contact between the upper end of fixed rod 4 and movable rod 3, fixed rod 4 and movable rod The lower ends of 3 are sharp ends, and the two sharp ends form a clamping end, forming a clip that is opened between the upper ends of the movable rod 3 and the fixed rod 4 and the lower ends are clamped;
[0020] The rear of the movable rod 3 is fixed with a reel 7 that rotates coaxially with the movable rod 3. There is a dial pin 8 on the end face of the reel 7, and there is a rotating pin on the frame body 1 that is located on one side of the reel 7. Cam 9, there is a flat plate 11 above the cam 9, the left end of the flat plate 11 is ...
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The invention discloses an isolated-heart perfusion device applicable to rats, effectively solving problems of existing perfusion devices, including insecurity in heart fixation and inaccuracy in insertion position of perfusion needles into aortas. The isolated-heart perfusion device comprises a frame. A fixed rod is fixed in front of the frame. A movable rod is hinged to the fixed rod. A clamp with open upper ends and clamped lower ends is formed by the movable rod and the fixed rod. A winding wheel is arranged in rear of a hinged position of the movable rod coaxially. A shifting pin is arranged on the end face of the winding wheel. A cam located on one side of the winding wheel is arranged on the frame. A plate is arranged above the cam. The lower surface of the right end of the plate contacts with the protrusion end of the cam. An open slot is formed in the other end of the cam. A cross beam capable of sliding leftwards and rightwards is arranged above the plate, and can slide up and down. A perfusion needle is arranged below the cross beam. An intermittent gear is fixed to the rear side of the winding wheel coaxially. A full gear is meshed with the right side of the intermittent gear. A shifting rod is fixed to the end face of the full gear. The upper end of the shifting rod penetrates the cross beam. The isolated-heart perfusion device has the advantages of novelty in thought, ingenious structure, simplicity in operation, and improved perfusion experiment efficiency.
Description
technical field [0001] The invention relates to the technical field of perfusion devices, in particular to an isolated heart perfusion device suitable for rats. Background technique [0002] In the isolated heart perfusion experiment, the heart of the animal is taken out, connected to a specific perfusion device, and perfused with perfusate, excluding the control of nerves and body fluids, with special analysis software to record ventricular pressure, arterial blood pressure and ECG signals, and automatically analyze various Physiological parameters, used in the study of cardiac function and hemodynamic changes under pathophysiological conditions, have been widely used in physiological, pathophysiological and pharmacological research. [0003] At present, when performing perfusion experiments on rat hearts, it is necessary to manually insert the perfusion needle into the aorta of the isolated heart, then temporarily fix the heart on the perfusion needle with an arterial clam...
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IPC IPC(8): G01N33/48
Inventor 张大伟程珊王琳赵越
Owner XINXIANG MEDICAL UNIV