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Small intestine acellular dermis matrix film combined metal net chest wall repairing material

An acellular matrix and repair material technology, which is applied in the field of small intestine acellular matrix membrane combined with metal mesh chest wall repair materials, and can solve problems such as injury, chest wall defect, and patient life-threatening

Inactive Publication Date: 2018-12-07
JILIN UNIV
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  • Application Information

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Problems solved by technology

[0002] In clinical practice, many patients with severe trauma have chest wall defects. When the defect area is large, it is easy to cause mediastinal oscillation, and the life of the patient is threatened. The conventional operation is only a partial repair, or a part of the tissue or organ from other parts of the body is used for repair. cause some damage

Method used

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  • Small intestine acellular dermis matrix film combined metal net chest wall repairing material
  • Small intestine acellular dermis matrix film combined metal net chest wall repairing material
  • Small intestine acellular dermis matrix film combined metal net chest wall repairing material

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Embodiment Construction

[0021] The present invention firstly provides a small intestine acellular matrix membrane combined with metal mesh chest wall repair material, the material includes two parts, small intestine acellular matrix membrane and metal mesh, its preparation method is as follows:

[0022] Step 1: Take a local white pig with a weight of 50-100Kg, use the preparation method of "Natural Tubular Small Intestine Acellular Matrix Membrane and Its Preparation Method" invented by our research group to prepare the natural tubular acellular matrix membrane of the small intestine, and then Cut it longitudinally to obtain a sheet of acellular matrix membrane.

[0023] Step 2: Use titanium-nickel alloy materials to make metal meshes of different sizes. The metal meshes have certain toughness and elasticity. After implanting in the chest wall, they cannot move with changes in the pressure difference between the inside and outside of the thoracic cavity. The diameters of titanium-nickel alloy wires u...

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Abstract

The invention provides a small intestine acellular dermis matrix film combined metal net chest wall repairing material and belongs to the field of medical biological materials. The material is prepared through the following steps: after processing a small intestine cut from an animal, preparing a small intestine acellular dermis matrix film; and then combining the small intestine acellular dermismatrix film with a metal net to prepare the chest wall repairing material. A preparation method of the material provided by the invention is simple and the obtained chest wall patch material is used for a patient with chest wall defects to repair the chest wall; and the chest wall repairing material has a wide application prospect.

Description

technical field [0001] The invention belongs to the field of medical biomaterials, and in particular relates to a small intestine acellular matrix membrane combined with metal mesh chest wall repair material. Background technique [0002] In clinical practice, many patients with severe trauma have chest wall defects. When the defect area is large, it is easy to cause mediastinal oscillation, and the life of the patient is threatened. The conventional operation is only a partial repair, or a part of the tissue or organ from other parts of the body is used for repair. At the same time, it caused some damage. With the progress of related research on small intestinal acellular matrix membrane (ECM) biological patch, our scientific research team has developed a small intestinal acellular matrix membrane combined with metal mesh chest wall repair material, which has a wide range of clinical applications and can be applied to the pleura, Repair of chest wall, skull, etc. The patc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/36A61L27/06A61L27/50
CPCA61L27/06A61L27/3633A61L27/365A61L27/50A61L2430/02
Inventor 冯永刚韩春山薛锦儒冯敏王图慧张乐宁孙宏斌崔建华张丽萍
Owner JILIN UNIV
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