Dicranostigma leptopodum pharmaceutical preparation and preparation method thereof
A technology of drug preparation and reincarnation, which is applied in the direction of drug combination, pharmaceutical formula, pill delivery, etc., can solve the problems of low active ingredient content and low drug loading capacity, and achieve the increase of protocatechuic acid content and drug loading capacity , Conducive to the effect of preparation molding and clinical medication
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Example Embodiment
[0042] Example 1
[0043] This embodiment prepares Lemahui tablets through the following steps
[0044] Decoct 3kg of the whole grass in 90℃ water for 2 times, add 6 times the amount of water for the first time and cook for 1 hour, add 4 times the amount of water for the second time, and cook for 0.5 hours. Combine the two decocted The decoction liquid is filtered and concentrated to obtain a concentrated liquid (relative density of 1.23). Add ethanol to the concentrated liquid to make the alcohol content reach 70%, add alcohol while stirring, let stand for 24 hours, filter the resulting precipitate, and concentrate the filtrate to a relative density of 1.35 , Add 0.4g magnesium stearate and 110g dextrin, mix well, granulate with an 18-mesh sieve, dry, granulate, and compress 1000 tablets, each weighing 0.22g. Each tablet contains 3g of drug.
Example Embodiment
[0045] Example 2
[0046] This embodiment prepares Lema drop pills by the following steps
[0047] Decoct 3kg of the whole grass in 85℃ water for two times, add 6 times the amount of water for the first time and cook for 1.5 hours, add 4 times the amount of water for the second time and cook for 1 hour, combine the two decocted The decoction liquid is filtered and concentrated to obtain a concentrated liquid (relative density of 1.23). Add ethanol to the concentrated liquid to make the alcohol content reach 70%, and let it stand for 18 hours. The precipitate is filtered to obtain the filtrate, which is concentrated to a relative density of 1.30 and dried to obtain Lemahui extract, and then mixed with PEG2000 3 times the quality of Lemahui extract, placed in a heating container to heat to form a molten state, using the temperature difference between the dropping pill machine and the coolant to shrink the molten molten liquid into a shape The dropping pills were prepared, and 10,000...
Example Embodiment
[0048] Example 3
[0049] This embodiment prepares Lemahui tablets through the following steps
[0050] Decoct 3kg of the whole grass in 80℃ water for two times, add 5.5 times the amount of water for the first time and cook for 1 hour, add 4 times the amount of water for the second time, and cook for 0.5 hours. Combine the two decocted The decoction liquid is filtered and concentrated to obtain a concentrated liquid (relative density of 1.20). Add ethanol to the concentrated liquid to make the alcohol content reach 70%, and let it stand for 18 hours. The precipitate is filtered to obtain the filtrate, which is concentrated to a relative density of 1.40 and dried to obtain Lemahui extract, then pulverize the Lemahui extract, pass a 100-mesh sieve, add an appropriate amount of 85% alcohol to make a soft material, use a 20-mesh sieve to make granules, ventilate and dry at 60℃, add magnesium stearate 0.35g, 0.05g silicon dioxide, 330g dextrin, granulated with an 18-mesh sieve, dried, ...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.
© 2023 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap