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Devices, systems and methods for detecting and monitoring inhalation

A technology for inhalers and accessories, applied in inhalers, applications, respirators, etc., can solve the problems of lack of efficacy in disease treatment and harm to patients

Active Publication Date: 2022-04-15
MANNKIND CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Improper use of devices and poor inhalation technique can lead to lack of efficacy in disease treatment
For example, administering lower or higher doses of a therapeutic substance than expected may be harmful to the patient

Method used

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  • Devices, systems and methods for detecting and monitoring inhalation
  • Devices, systems and methods for detecting and monitoring inhalation
  • Devices, systems and methods for detecting and monitoring inhalation

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0092] Use the integrated training device

[0093] A 60-year-old patient with type 1 diabetes was instructed to receive dietary therapy of inhaled insulin delivered from a dry powder inhalation system because the patient had elevated hemoglobin A1c and was considered out of control. The patient uses an insulin pump with basal insulin. The patient uses as figure 1 The device shown in is trained for wireless inhalation with features such as Figure 3 to Figure 5 Removable suction attachment shown in . The device is provided to the patient and the patient is asked to take quick, deep breaths while using the training device which may or may not include medication.

[0094] A pressure sensor on the inhalation device is used to detect the pressure drop during inhalation, and the data is transmitted to a Bluetooth-enabled tablet with an associated app. A color detection sensor detects the color of the cartridge (with substance or empty) and the data is used to identify a thresh...

example 2

[0097] Use the attachable training device

[0098] A 59-year-old type 2 diabetic patient was instructed to receive inhaled insulin from a dry powder inhalation system. The patient requests the use of the inhalation system for reasons of convenience. The patient uses as figure 1 The device shown is trained for wireless inhalation. Provide patients with equipment similar to Figure 3 to Figure 5 of the attachable inhaler device shown in figure 1 device, and ask the patient to take quick, deep breaths using the training device.

[0099] Pressure and color-coded data is collected on the mobile phone and the patient can view the data in real-time on the display. The patient's first attempt is acceptable as indicated by the threshold and inhalation data plotted or otherwise visually indicated as software results. After acclimatization, the patient understands how to use the device.

[0100] Remove the patient-attachable sensor from the dry powder inhaler. A patient is prov...

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PUM

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Abstract

Described herein is an interactive device and method for sensing and measuring real-time characteristic patterns of use of a dry powder inhalation system by a subject. The inhaler device may be used in a wireless communication mode to communicate with a display to assess the subject's use of the inhalation system while performing an inhalation, and thereby assess the subject's inhalation and the resulting inhalation. performance of the inhalation system. The system can also detect the identity of the drug, its dose, batch number, expiration time, etc., and the characteristic curve of the dry powder formulation issued from the inhalation system used.

Description

[0001] Cross References to Related Applications [0002] This application claims the benefit of US Provisional Patent Application No. 62 / 338,971, filed May 19, 2016, the entire disclosure of which is incorporated herein by reference. technical field [0003] Described herein are interactive devices and methods for recording, transmitting and displaying physical measurements based on physiological conditions of a subject generated during real-time inhalation maneuvers. Background technique [0004] Inhaler devices are commercially available for dispensing therapeutic substances via the respiratory tract, especially for pulmonary administration in the treatment of local or systemic diseases. For example, nebulizers, propellant-containing devices, and dry powder inhalers have been used to treat diseases such as asthma, respiratory infections, and systemic diseases such as diabetes. [0005] In disease treatment, the effectiveness of delivering the desired dose of therapeutic s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M15/00
CPCA61M15/0028A61M15/008G09B5/02A61K38/28A61M15/0065G09B23/28A61K47/22A61M2205/3306A61M2205/3569A61M2205/3344A61M2205/6018A61M2205/3368A61M16/161A61M2205/3584A61M15/0021A61M15/0043A61M2205/3561A61M2205/6054A61M2016/0033A61M2205/13A61M2016/0027A61M2202/064A61M2205/52A61B5/087A61M2205/50A61M2205/3358A61M2205/587A61M2205/3553A61M2205/3313A61M2205/502A61M2205/8206A61M2205/3592A61M2205/3331A61M2205/3375A61M2016/0021A61M2205/6063A61M2205/583A61M2230/40A61M2205/6081A61B2562/08A61M2206/10
Inventor 约翰·J·波可瑞瓦三世班诺特·阿达莫布伦丹·劳伦茨查得·C·斯穆尼P·斯宾塞·金赛
Owner MANNKIND CORP