The application of atxn2l as a marker for auxiliary evaluation of secondary resistance to oxaliplatin in gastric cancer
An oxaliplatin and secondary technology, which is applied in the function and application of genes and proteins, and can solve problems affecting the efficacy of chemotherapy, etc.
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[0016] 1. Experimental materials
[0017] 1. Tissue specimens
[0018] Tissue section: Gastric cancer resection specimens were selected from Nanfang Hospital of Guangzhou Southern Medical University, including radical resection and palliative resection.
[0019] The inclusion criteria for pathological slides were: 1. Gastric cancer was confirmed by pathology; 2. Pathological slides were from the primary tumor of the stomach.
[0020] Exclusion criteria for pathological slides were: 1. Controversial pathological diagnosis; 2. Incomplete clinical treatment.
[0021] According to the patient's intraoperative condition and imaging examination, the patient was classified into TNM staging. According to the above criteria, a total of 48 cases of stage IV and 119 cases of stage I-III gastric cancer tissue samples were included for analysis. The samples were fixed with 10% formalin, embedded in paraffin, and sectioned.
[0022] Fresh gastric cancer specimens: Gastric cancer surgical...
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