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Natural biomaterials for near-infrared light excitation response, their preparation methods and applications
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A biological material and near-infrared light technology, which can be applied in the fields of wave energy or particle radiation treatment materials, medical preparations containing active ingredients, pharmaceutical formulations, etc. Effect
Active Publication Date: 2021-09-03
WENZHOU UNIV
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Nanoparticles of photothermal materials mainly include metal nanoparticles, organic nanoparticles, and inorganic nanoparticles, but there is no specific literature or monograph on the photothermal properties of natural biological materials.
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preparation example Construction
[0035] This embodiment provides a kind of natural biological material used for near-infrared light excitation response, and its preparation method includes the following steps:
[0036] S100, degreasing the natural pollen.
[0037] Degreasing the natural pollen in the first solvent, removing the solvent containing the ester after degreasing, washing with the first solvent and drying.
[0038] Wherein, the natural pollen includes any one or a mixture of natural sunflower pollen, dandelion pollen, wolfberry pollen, rape flower pollen and natural pine pollen. The dosage ratio of natural pollen to the first solvent is 1g:10-15ml; too much solution will increase the dosage of solvent and increase the cost of the experiment, and too little solvent will result in insufficient degreasing. Preferably, the first solvent includes one or a mixture of diethyl ether, ethyl acetate, and acetone.
[0039] In this embodiment, the first solvent is used for washing several times, for example, ...
Embodiment 1
[0054] Take 20g of dried natural sunflower pollen in a round bottom flask, add 200ml of ether, stir overnight at room temperature under a relative centrifugal force of 600g, remove ether by suction filtration, wash with ether three times, dry at 60°C to obtain defatted natural sunflower pollen, and store at room temperature .
Embodiment 2
[0056] Take 20g of dried natural sunflower pollen in a round bottom flask, add 250ml of ether, stir overnight at room temperature under a relative centrifugal force of 600g, remove the ether by suction filtration, wash with ether three times, dry at 60°C to obtain defatted natural sunflower pollen, and store at room temperature .
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Abstract
The invention relates to the field of photothermal materials, and provides a natural biological material for near-infrared light excitation response, a preparation method and application thereof. The preparation method includes degreasing the natural pollen in a first solvent, removing the ester-dissolved solvent after degreasing, washing with the first solvent and drying. The obtained natural biological material for near-infrared light excitation response is a pure natural biological material, which has good heating performance under near-infrared laser irradiation, and the material can be repeatedly heated under near-infrared light, with good heating performance. Heating performance. At present, few people propose to use natural biological materials as photothermal therapy materials. In the present application, natural pollen is processed to form degreasing natural pollen, and it is used as photothermal therapy material, providing a new photothermal therapy material.
Description
technical field [0001] The invention relates to the field of photothermal materials, in particular, to a natural biological material used for near-infrared light excitation response, its preparation method and application. Background technique [0002] Tumor is a disease that mainly threatens human life and health. Traditional tumor treatment methods include tumor resection, biological therapy, traditional Chinese medicine treatment, chemical drug therapy, and radiation therapy. However, each treatment method has some limitations. With the continuous progress of social science, the rapid development of laser and near-infrared technology, the rapid development of research on the method of treating tumors through nanomedicine. As a minimally invasive tumor treatment technology, photothermal therapy has high specificity, can target tumors, and has good biocompatibility. It can use near-infrared excitation light as a light source to excite nanoparticles and convert the light sou...
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