Method for determining internal irradiation delay score of mixed intake mother-daughter nuclide
A technology of daughter nuclide and determination method, applied in the fields of medical informatics, medical simulation, computer-aided medical procedures, etc., can solve the problems of undiscovered patents and documents, and achieve the effect of strong versatility and expansion of application scope.
Active Publication Date: 2019-07-09
63653 FORCES PLA
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The comparative analysis of the literature shows that the method proposed by the present invention has not found any patents and literatures with the same principles as the invention in the relevant domestic fields.
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[0024] The best way to implement the invention is as follows:
[0025] (For the convenience of description, the following is a simple case of two nuclides - nuclide A decays to produce nuclide B. For the case of more nuclides, it can be deduced by analogy.
[0026] (1) Establish a suitable biokinetic model
[0027] According to the method in the technical scheme (1), the single nuclide model of the daughter nuclide B is established, which is denoted as model I. According to the method in the technical scheme (2), a mixed decay model of parent nuclide A and daughter nuclide B is established, which is denoted as model II.
[0028] (2) Solve the established biokinetic model
[0029] According to the proportional relationship of the two nuclides in the environment, different initial conditions are set for the two sets of models I and II, and then the first-order ordinary differential equations numerical solution method is used to solve the problem.
[0030] (3) Calculation of n...
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The invention is mainly used for the field of internal irradiation dosage monitoring and evaluation in irradiation protection, and provides a method for determining an internal irradiation delay scoreof a mixed intake mother-daughter nuclide. The method is characterized by: (1) a single-nuclide biological dynamic model, wherein in-vitro transferring of a radionuclide after intake is presented bymeans of a transferring isolation storeroom which is recommended by an internal commission on radiological protection (ICRP); (2), a mother-daughter decay containing biological dynamics model, whereinabsorbing, transferring and excretion of the mother-daughter nuclide in the human body should be described by means of a mother nuclide and daughter nuclide mixed biological dynamic model; and (3), initial mixing of intake mother-daughter nuclide, when the mother nuclide and the daughter nuclide coexist in an initial environment, the mother-daughter mixed nuclide is intake into the body. The method can calculate a delay score on the condition of mixed intake mother-daughter nuclide and mother-daughter nuclide decaying, thereby laying a foundation for internal irradiation monitoring and dosagecalculation.
Description
technical field [0001] The invention is mainly used in the field of internal radiation dose monitoring and evaluation in radiation protection. Background technique [0002] The human biokinetic model describes the metabolic transfer behavior of nuclides in the human body (including intake, deposition, absorption, retention, and excretion), and the distribution and retention of nuclides in the human body are important factors that determine organ doses, so retention The determination of the score is the basis for internal radiation monitoring and dose calculation. The general biokinetic model method can only deal with the intake of a single radionuclide, and for the complex nuclide model, it can only deal with the kinetic process of the parent nuclide, and cannot simultaneously deal with the metabolic process of the daughter nuclide produced by the decay of the parent . This directly affects the accuracy and completeness of internal radiation monitoring and dose calculation...
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Inventor 不公告发明人
Owner 63653 FORCES PLA