Method for regulating and controlling crystal habits of propyzamide with solvent
A technology for regulating pentynclochlor and solvent, which is applied in the fields of organic chemistry methods, separation/purification of carboxylic acid amides, organic chemistry, etc., and can solve problems such as non-uniform crystal habit of pentynclochlor
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specific Embodiment approach 1
[0032] Specific implementation mode one: this implementation mode is a method for solvent regulation and control of the crystal habit of fenpyrald, which is specifically completed according to the following steps:
[0033] 1. Configure saturated solution: at temperature T 0 down, follow T 0 The mass ratio of pentarynclod in the solvent is a saturated solution when pentarynclod is added to the solvent to obtain a saturated solution of pentarynclod; 298.15K0 ≤328.15K;
[0034] 2. Heating treatment: transfer the saturated solution of pentynchlor to the crystallizer, adjust the water bath to make the temperature from T 0 Raise 5~10K to T 1 , at temperature T 1 Keep it down for 60 minutes;
[0035] 3. Crystallization: adjust the water bath to make the temperature from T 1 Decrease until it is in the metastable zone, and the solute molecules are nucleated and precipitated, at this time the temperature is T 2 , and then under the condition that the supersaturation is kept const...
specific Embodiment approach 2
[0036] Embodiment 2: The difference between this embodiment and Embodiment 1 is: the crystal habit of the pentoxychlor crystals described in step 1 is a needle-like crystal habit, and the solvent is an aromatic solvent. Others are the same as the first embodiment.
specific Embodiment approach 3
[0037] Embodiment 3: The difference between this embodiment and Embodiment 2 is that the aromatic solvent is benzene, toluene or xylene. Others are the same as in the second embodiment.
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