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Pharmaceutical composition for treating psoriasis and preparation method thereof

A technique for psoriasis and composition, which is applied in the field of pharmaceutical composition for treating psoriasis and its preparation, can solve the problems of drug withdrawal and easy recurrence, and achieve the treatment of psoriasis, the preparation method is simple and easy to operate, and the treatment effect is good Effect

Active Publication Date: 2019-11-12
北京市中医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Biological agents and targeted inhibitors, such as currently approved drugs including etanercept, inflixi, adalimide, etc., regulate the inflammatory response by inhibiting cytokine receptors and their pathways on the target, but there are also Problems prone to relapse after drug withdrawal

Method used

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  • Pharmaceutical composition for treating psoriasis and preparation method thereof
  • Pharmaceutical composition for treating psoriasis and preparation method thereof
  • Pharmaceutical composition for treating psoriasis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0062] The preparation method of the pharmaceutical composition for treating psoriasis as described above, comprises the following steps:

[0063] Mix each drug component with water and extract by heating;

[0064] The heating extraction includes decocting with strong fire and then decocting with slow fire to obtain the extraction liquid.

[0065] In the present invention, the medicinal components are mixed with water, then heated and extracted, and decocted with strong fire, so that the temperature rises quickly and the water evaporates quickly; decoction with slow fire can prevent the rapid evaporation of medicine gas; through the combination of slow fire and strong fire, each medicinal material can be The active ingredients in it are better dissolved into the water.

[0066] Preferably, the weight ratio of the pharmaceutical component to the water is 1:(5-8).

[0067] Using an appropriate amount of water can better decoct the medicine.

[0068] In one embodiment, the wei...

Embodiment 1

[0104] A pharmaceutical composition for treating psoriasis, the raw material components are as follows:

[0105] Hedyotis diffusa 30g, Smilax smilax 30g, Saffron 30g, Comfrey 10g, Gentiana 3g, Scutellaria baicalensis 10g, buffalo horn 15g, raw Sophora japonica 10g and white fresh bark 10g;

[0106] The preparation method of the pharmaceutical composition for the treatment of psoriasis, comprises the following steps:

[0107] (a) Mix Hedyotis diffusa, Smilax smilax, Saffron, Comfrey, Gentiana, Scutellaria baicalensis, buffalo horn, raw Sophora japonica and white fresh skin, add water to soak for 30 minutes, first decoct with strong fire for 5 minutes, Then decoct with slow fire for 25 minutes, and filter to obtain the medicinal liquid;

[0108] The weight ratio of the pharmaceutical component to the water is 1:6;

[0109] (b) adding water to the medicinal dregs in step (a), decocting with a slow fire for 30 minutes, collecting twice the medicinal liquid and concentrating toge...

Embodiment 2

[0113] A pharmaceutical composition for treating psoriasis, the raw material components are as follows:

[0114] Hedyotis diffusa 20g, Smilax tuckahoe 40g, Saffron 20g, Comfrey 15g, Gentiana 6g, Scutellaria baicalensis 5g, buffalo horn 20g, raw Sophora japonica 10g and white fresh bark 15g;

[0115] The preparation method of the pharmaceutical composition for the treatment of psoriasis, comprises the following steps:

[0116] (a) Mix Hedyotis diffusa, Smilax smilax, Saffron, Comfrey, Gentiana, Scutellaria baicalensis, buffalo horn, raw Sophora japonica and white fresh skin, add water to soak for 20 minutes, first decoct with strong fire for 8 minutes, Then decoct with slow fire for 35 minutes, and filter to obtain the medicinal liquid;

[0117] The weight ratio of the pharmaceutical component to the water is 1:6;

[0118] (b) adding water to the medicinal residues in step (a), decocting with a slow fire for 20 minutes, collecting twice the medicinal liquid and concentrating to...

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Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating psoriasis and a preparation method thereof. The pharmaceutical composition for treating psoriasis comprises the following active components in parts by weight: 20-40 parts of oldenlandia diffusa, 20-40 parts of glabrous greenbrier rhizome and 20-40 parts of prince's-feather fruits. The active components have excellent effects of clearing away heat and toxic materials, eliminating dampness and removing blood stasis, and can well treat psoriasis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating psoriasis and a preparation method thereof. Background technique [0002] Psoriasis is a common chronic autoimmune disease in dermatology, with erythema and scales as typical clinical skin lesions. The pathogenesis of psoriasis is still unclear, and genetic predisposition and environmental factors are the main predisposing factors. In the context of polygenic inheritance, the interaction between immune cells and their related cytokines and chemokines mediates a series of inflammatory responses, resulting in changes such as epidermal proliferation, parakeratosis, and acanthosis. [0003] Psoriasis currently has no effective cure for psoriasis drugs and methods, commonly used clinical treatment measures can be divided into physical therapy, local drug therapy and systemic drug therapy. Physiotherapy and l...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61P17/06A61K35/32
CPCA61K35/32A61K36/076A61K36/185A61K36/232A61K36/30A61K36/481A61K36/486A61K36/489A61K36/515A61K36/539A61K36/54A61K36/65A61K36/704A61K36/71A61K36/736A61K36/748A61K36/75A61K36/896A61K36/90A61K2236/331A61K2236/39A61P17/06A61K2300/00
Inventor 李萍底婷婷王燕付京郭肖瑶翟春艳
Owner 北京市中医研究所