Synthetic method for methyl ethyl ketoxime
A synthesis method and technology of butanone oxime, applied in the field of compound synthesis, can solve problems such as short time consumption, and achieve the effects of short time consumption, low pollution and high yield
Inactive Publication Date: 2020-01-03
王小桥
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Problems solved by technology
[0003] The purpose of the present invention is to solve the above-mentioned problems in the existing synthetic method of butanone oxime, and provide a kind of synthetic method of butanone oxime that is easy to operate, has little pollution, high yield and short time consumption
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[0007] In this example, 50 g of methyl ethyl ketone was added to a 250 mL flask, and 95 g of 50% ethanol solution of hydroxylamine hydrochloride was added dropwise into a constant pressure dropping funnel, stirred and heated to 58° C., kept for 90 minutes, cooled and filtered, and the filtrate was heated and distilled to collect fractions at 152-154° C. That is butanone oxime.
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The invention discloses a synthetic method for methyl ethyl ketoxime. The method comprises the following steps: adding a hydroxylamine hydrochloride ethanol solution dropwise into butanone, performingheating under stirring to 50-60 DEG C, performing an oximation reaction for 1-2 h, performing cooling, performing filtration, heating a filtrate, performing distillation, and collecting the fractionat 152-154 DEG C to obtain the methyl ethyl ketoxime. The method has the advantages of simple synthetic conditions, convenient operation, small pollution, a high yield, and short consumed time.
Description
technical field [0001] The invention belongs to the field of compound synthesis, in particular to a method for synthesizing butanone oxime. Background technique [0002] The present synthesis methods of butanone oxime include: 2-nitrobutane catalytic hydrogenation method, electrochemical method, oxime exchange method, etc. Some of these methods are highly polluting, some have low yields, and some take a long time. Contents of the invention [0003] The purpose of the present invention is to solve the above-mentioned problems in the existing synthetic method of butanone oxime, and provide a synthetic method of butanone oxime with convenient operation, low pollution, high yield and short time consumption. [0004] The present invention is realized through the following technical scheme: add hydroxylamine hydrochloride ethanol solution dropwise to methyl ethyl ketone, stir and heat up to 50-60°C, oximation reaction time is 1-2h, cool and filter, heat up the filtrate and disti...
Claims
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IPC IPC(8): C07C249/08C07C251/38
CPCC07C249/08C07C251/38
Inventor 王存亮许灵艳严学文黄焕军王小桥
Owner 王小桥