A 3D bioprinting device suitable for gradient structured multi-materials

Abstract

The invention discloses a biological 3D printing device suitable for multi-materials with a gradient structure, which belongs to the field of rapid manufacturing of medical devices. In this device, the three-dimensional motion unit of the manipulator is placed inside the incubator, which drives the nozzle to make three-dimensional movements in the XYZ direction in the upper biological fluid in the forming box to perform 3D bioprinting; the hydraulic unit is placed inside the incubator, and the inlet pipe is connected to the hydraulic pump and At the bottom of the forming box, the outlet pipe extends in accordance with the three-dimensional motion unit of the manipulator, and connects with the hydraulic pump and the nozzle. The hydraulic pump pumps out the biological fluid at the bottom of the forming box and sends it to the nozzle; sensors and auxiliary units are used to monitor and adjust the internal environment of the incubator; control And the data processing unit is used to control the work of the three-dimensional motion mechanism of the manipulator and the hydraulic unit, and at the same time receive and process the monitoring data provided by the sensor and the auxiliary unit. The invention has high degree of automation, high green and low-carbon efficiency, and wide effective use space, and has great significance for realizing temperature gradient control of biological materials.

Description

technical field [0001] The invention belongs to the field of rapid manufacturing of medical devices, and more specifically, relates to a new bio-3D printing comprehensive molding system that uses multi-manipulators to support multi-nozzle movement and hydraulic pump technology to provide biological fluids, and is suitable for bio-3D printing with gradient structures and multi-materials Research. Background technique [0002] Traditional biological 3D printers rely too much on long-distance linear moving parts such as lead screws, optical axes, and linear guides, which restricts the printing space in the effective forming area and has a low degree of automation; conventional biological 3D printing nozzles adopt a syringe-type structure, and the volume of the syringe is limited The one-time molding rate of large-sized biological structural parts is reduced, and the efficiency is low, and the working environment is not easy to control, which affects the survival rate of biologi...

AI Technical Summary

Problems solved by technology

[0003] Aiming at the above defects or improvement needs of the prior art, the present invention provides a biological 3D printing device suitable for multi-materials with gradient structure. And the technical problem that the temperature of the working environment is not easy to control

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