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Automatic reversible skin dredging device

A skin, automatic technology, applied in hypodermic injection devices, needles, devices introduced into the body, etc., can solve the problems of manual operation, low efficiency, stratum corneum damage, etc., to promote drug penetration and absorption, improve safety, Well-designed effects

Active Publication Date: 2020-04-07
SUZHOU NANOMED BIOMED CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the existing equipment equipped with microneedles to rupture the stratum corneum can only be operated manually, which is cumbersome and inefficient; even if there is an electric drive, it is only in the electric vibration mode, which cannot evenly dredge the stratum corneum of the skin , resulting in uneven delivery of therapeutic agents and other active ingredients to the epidermis; in addition, the existing devices equipped with microneedles to rupture the stratum corneum have the microneedles to cut the stratum corneum laterally during operation, which poses a relatively large impact on the stratum corneum. Large damage causes the stratum corneum to fail to recover automatically within a short period of time after dredging, reducing the protective barrier function of the stratum corneum

Method used

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  • Automatic reversible skin dredging device
  • Automatic reversible skin dredging device
  • Automatic reversible skin dredging device

Examples

Experimental program
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Embodiment 1

[0028] like Figure 1-4As shown, an automatic skin dredging device includes: a base 1, a housing 30, a control mechanism, and a power module 12; the power module 12 is fixedly arranged on the base 1; the first drive motor 2, the first gear 3 , the longitudinal movement mechanism that the second gear 4, the first leading screw 5, the longitudinal movement slider 6, the first left guide support rod 7, and the first right guide support rod 8 constitute; the output shaft of the first drive motor 2 The first gear 3 is fixedly connected, the second gear 4 meshes with the first gear 3, and the two ends of the first screw mandrel 5 are not provided with threads, and one end of the first screw mandrel 5 is used as the gear shaft of the second gear 4; The longitudinally moving slide block 6 is provided with an internally threaded hole matched with the first screw mandrel 5 and a through hole matched with the left first guide support bar 7 and the right first guide support bar 8; Bar 5 ...

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Abstract

The invention discloses an automatic reversible skin dredging device which comprises a micro instrument, a base, a shell and a control mechanism. A longitudinal moving mechanism, a transverse moving mechanism, a vertical moving mechanism and a power module are arranged in the shell. The base is provided with a working area where the micro instrument makes contact with the skin. The micro instrument can realize longitudinal movement, transverse movement and vertical movement. According to the invention, higher efficiency of automatic dredging of skin can be realized, uniform conduction of skincuticle in a designated area is realized, and medicine permeation and absorption are promoted to be better. In addition, the micro needle can be prevented from being transversely scratched during skindredging; self-recovery of the skin can be realized within short time; and the safety of transdermal drug delivery is further improved.

Description

technical field [0001] The invention relates to an automatic reversible skin dredging device, which belongs to the technical field of transdermal drug delivery. Background technique [0002] Drugs are usually administered in solid form via pills or capsules that can be taken orally. However, many biological drugs cannot be administered in this way due to degradation in the gastrointestinal tract and rapid elimination by the liver. Another common technique for administration of liquid form drugs is by injection using metal hypodermic needles, which can cause significant pain and discomfort to the patient. Many physical and chemical techniques including electroporation, laser ablation, ultrasound, heat, iontophoresis, and chemical enhancers have been explored to develop painless transdermal drug delivery techniques. It has been found that molecules with a molecular weight higher than 500 or a diameter larger than 1 nm have difficulty penetrating normal human skin. Further s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00
CPCA61M37/00A61M37/0015A61M2037/0007A61M2037/0023A61M2205/33
Inventor 徐百
Owner SUZHOU NANOMED BIOMED CO LTD
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