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Ginkgo composite polyphenol plant medicine for treating hyperlipidemia and coronary heart disease and preparation method of medicine

A technology for hyperlipidemia and coronary heart disease, applied in the field of drug development and biological fermentation, can solve problems such as poor curative effect, lowering LDL, and life-threatening

Inactive Publication Date: 2020-05-01
GUOZHONGXINGHE BIOMEDICINE TECH CO LTD +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The former has a definite therapeutic effect on hypercholesterolemia, significantly lowering LDL, and at the same time has no effect on HDL or slightly increases it. While treating hyperlipidemia, it has a significant therapeutic effect on atherosclerosis; the latter is to reduce glycerol Most effective drug on triglyceride (TG) level, less effective on LDL-C
Although the efficacy of these drugs has been confirmed, the incidence of adverse reactions is relatively high, especially for the simultaneous treatment of high cholesterol and hypertriglyceridemia, the combined use of these two drugs can cause life-threatening serious adverse reactions such as rhabdomyolysis

Method used

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  • Ginkgo composite polyphenol plant medicine for treating hyperlipidemia and coronary heart disease and preparation method of medicine
  • Ginkgo composite polyphenol plant medicine for treating hyperlipidemia and coronary heart disease and preparation method of medicine
  • Ginkgo composite polyphenol plant medicine for treating hyperlipidemia and coronary heart disease and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] In parts by weight, the Ginkgo compound polyphenol herbal medicine for the treatment of hyperlipidemia and coronary heart disease in this embodiment includes: 20 parts of Ginkgo leaf extract, Agaricus Blazei 10 parts of powder, 5 parts of pea powder, 3 parts of heterophylla, 3 parts of Chuanxiong, 10 parts of gardenia fruit oil, 2 parts of cassia seed, 5 parts of astragalus, 5 parts of salvia miltiorrhiza, 3 parts of angelica, 3 parts of yeast dextran, 2 parts of rehmannia glutinosa 5 parts of linseed oil, 1 part of wolfberry, 2 parts of onion extract, 5 parts of xylitol.

[0056] Further, Ginkgo extract has been widely used in medicines, health care products and cosmetics. According to research, it is known that there are more than 170 kinds of medicinal ingredients of Ginkgo biloba, including: flavonoids, terpene lactones, organic acids, amino acids, sugars, alcohols, trace elements and others, of which terpene lactones and flavonoids It is the main active ingredient...

Embodiment 2

[0084] The only difference between this example and Example 1 is that, in parts by weight, the Ginkgo compound polyphenol botanical drug for the treatment of hyperlipidemia and coronary heart disease in this example consists of the following components: 25 parts of Ginkgo leaf extract , 12 parts of Agaricus blazei powder, 8 parts of pea powder, 5 parts of heterophylla, 5 parts of Chuanxiong, 15 parts of gardenia fruit oil, 3 parts of cassia seed, 8 parts of astragalus, 8 parts of salvia miltiorrhiza, 5 parts of angelica, 5 parts of yeast dextran , 3 parts of Rehmannia glutinosa, 8 parts of linseed oil, 2 parts of wolfberry, 3 parts of onion extract, 8 parts of xylitol, and 58 parts of water.

Embodiment 3

[0086] The only difference between this example and Example 1 is that, in parts by weight, the Ginkgo compound polyphenol botanical drug for the treatment of hyperlipidemia and coronary heart disease in this example consists of the following components: 22 parts of Ginkgo biloba extract , 11 parts of Agaricus blazei powder, 7 parts of pea powder, 4 parts of heterophylla, 4 parts of Chuanxiong, 13 parts of gardenia fruit oil, 2.5 parts of cassia seed, 7 parts of astragalus, 6 parts of salvia miltiorrhiza, 4 parts of angelica, 4 parts of yeast dextran , Rehmannia glutinosa 2.5 parts, linseed oil 7 parts, wolfberry 1.5 parts, onion extract 2.5 parts, xylitol 7 parts, water 60 parts.

[0087]

[0088] Firstly crush the dried ginkgo leaves, first use 5 times the weight of ginkgo leaves in 85% ethanol for 3 hours, then use 2 times the weight of ginkgo leaves in 85% ethanol for 2 hours, repeat the first step The second extraction process was once, the extracts were combined, filter...

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Abstract

The invention discloses a ginkgo composite polyphenol plant medicine for treating hyperlipidemia and a coronary heart disease and a preparation method of the medicine. The medicine comprises the following components in parts by weight: 20-25 parts of ginkgo leaf extract, 10-12 parts of agaricus blazei powder, 5-8 parts of pea meal, 3-5 parts of radix pseudostellariae, 3-5 parts of rhizoma ligustici Chuanxiong, 10-15 parts of gardenia fruit oil, 2-3 parts of cassia seed, 5-8 parts of milkvetch root, 5-8 parts of danshen root, 3-5 parts of radix angelicae sinensis, 3-5 parts of yeast glucan, 2-3parts of prepared rehmannia root, 5-8 parts of linseed oil, 1-2 parts of fructus lycii, 2-3 parts of onion extract, and 5-8 parts of xylitol. Through reasonable compounding of the ginkgo leaf extract, the gardenia fruit oil and other components with hypoglycemic and lipid-lowering effects, the medicine which is suitable for people with hyperlipidemia, high thrombosis and atherosclerosis and can have the effects of reducing blood lipid, activating blood circulation and dissolving thrombus, preventing and curing atherosclerosis, and losing weight is obtained.

Description

technical field [0001] The invention relates to the fields of drug development and biological fermentation. More specifically, the present invention relates to a ginkgo compound polyphenol botanical medicine for treating hyperlipidemia and coronary heart disease and a preparation method thereof. Background technique [0002] Cardiovascular disease is one of the most common and serious diseases that endanger human health (especially middle-aged and elderly people), and hyperlipidemia (commonly known as hyperlipidemia) caused by lipid metabolism disorders Important risk factors for other cardiovascular and cerebrovascular diseases. Lowering blood lipids can reduce the incidence and mortality of these diseases, and has a positive effect on the prevention and treatment of cardiovascular and cerebrovascular diseases. Therefore, the prevention and treatment of hyperlipidemia has attracted more and more attention. [0003] Hyperlipidemia is characterized by changes in various lip...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61K9/48A61P3/06A61P9/10A61P7/02
CPCA61K9/4858A61K36/07A61K36/16A61K36/232A61K36/236A61K36/36A61K36/48A61K36/481A61K36/482A61K36/537A61K36/55A61K36/744A61K36/804A61K36/815A61K36/8962A61K2236/19A61K2236/331A61K2236/55A61P3/06A61P7/02A61P9/10A61K2300/00
Inventor 何静仁李玉保
Owner GUOZHONGXINGHE BIOMEDICINE TECH CO LTD
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