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Pharmaceutical composition for treating ulcerative colitis

A technology for ulcerative colitis and a composition, which is applied in the field of traditional Chinese medicine compositions, can solve the problems of complex chemical components, large doses taken by patients, and difficulty in controlling the extraction process of active components in the origin of raw materials, so as to achieve the effect of improving the effect and relieving weight loss. Effect

Active Publication Date: 2020-08-14
GUANGZHOU UNIVERSITY OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, due to the complex chemical composition of the Chinese medicine compound, which contains a large amount of ineffective ingredients, the patient's dosage is large
At the same time, factors such as the place of origin of the raw material drug and the extraction process of the active ingredient are difficult to control, which directly affects the stability of the drug quality.

Method used

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  • Pharmaceutical composition for treating ulcerative colitis
  • Pharmaceutical composition for treating ulcerative colitis
  • Pharmaceutical composition for treating ulcerative colitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] (2) Prescription: Nodosin 4g, Pitrine F 6g.

[0054] (3) Preparation method:

[0055] Take Nodosin and bitterwood F, add 30g of starch, 10g of dextrin, 8g of sucrose and an appropriate amount of 65% ethanol, mix evenly, granulate, dry to obtain granules, sieve and granulate, add 0.5g of micropowder silica gel, mix evenly, and press into plain tablet.

Embodiment 2

[0057] (1) Recipe: Nodosin 5g, Pitrine F 5g.

[0058] (2) Preparation method:

[0059] Take Nodosin and bitterwood F, add CMC-Na 24g, L-HPC 8g, PVP 25g, CMS-Na 5g and an appropriate amount of 65% ethanol to prepare soft materials, pass through a sieve, dry at 60°C to obtain granules, and sieve for granulation Finally, it is packaged into granules by packaging equipment.

Embodiment 3

[0061] (1) Prescription: Nodosin 3g, Pitrine F 7g.

[0062] (2) Preparation method:

[0063] Take Nodosin and bitterwood F, add 60g of honey, 50g of rice paste, 30g of batter and an appropriate amount of 65% ethanol to prepare a soft material, and then press it into a pill.

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Abstract

The invention relates to a pharmaceutical composition for treating ulcerative colitis. The pharmaceutical composition is composed of effective components and medically acceptable auxiliary materials,and is characterized in that the effective components are composed of the following raw materials in percentage by weight: 30-60% of Nodosin and 40-70% of picrasma quassioides alkali F. The inventionalso relates to a preparation method of the pharmaceutical composition. The effective components Nodosin and picrasma quassioides alkali F in the pharmaceutical composition show an obvious synergisticeffect in the aspect of treatment ulcerative colitis, so that the effect of treatment ulcerative colitis is obvious.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a medical preparation containing a raw material with a clear structure, in particular to a medicine for treating ulcerative colitis. Background technique [0002] Ulcerative colitis is a chronic intestinal inflammatory disease, the main features of which are intestinal inflammation and destruction of intestinal epithelial structure. , the disease is chronic, repeated and protracted, lacks specific measures in treatment, and has the threat of canceration. It is listed as one of the world's intractable diseases. Ulcerative colitis is a common disease in North America and Europe, but in recent years, the trend of increasing in our country is very obvious, and it has become a common disease of the digestive system. [0003] The pathogenesis of ulcerative colitis is still not completely clear. At present, it is believed that the disease may be the result of a combination ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4375A61K31/366A61K36/53A61K36/185A61P1/04
CPCA61K31/366A61K31/4375A61K36/185A61K36/53A61P1/04A61K2300/00
Inventor 林朝展祝晨蔯刘方乐卢增辉
Owner GUANGZHOU UNIVERSITY OF CHINESE MEDICINE