Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Vitamin detector quality control material composition and application thereof

A vitamin and composition technology is applied in the field of quality control of vitamin inspection items, which can solve the problems of high maintenance cost, high technical requirements, complex structure, etc., and achieve the effects of low detection cost, simple and fast operation, and stable chemical properties.

Pending Publication Date: 2020-09-25
中彦医疗科技有限责任公司
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, it is particularly important to simultaneously determine the content of multiple vitamins. High performance liquid chromatography (high performance liquid chromatography, HPLC) and liquid chromatography-tandem mass spectrometry (liquid chromatography-tandem mass spectrometry, LC-MS / MS) can simultaneously determine multiple vitamins. However, due to factors such as expensive instruments, high maintenance costs, complex structures and high technical requirements for operators, this method is limited in the popularization of this method in clinical vitamin monitoring.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Vitamin detector quality control material composition and application thereof
  • Vitamin detector quality control material composition and application thereof
  • Vitamin detector quality control material composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 Vitamin detector quality control product composition

[0023] 2,3,5,6-Tetramethyl-1,4-phenylenediamine: salt solution;

[0024] The concentration of 2,3,5,6-tetramethyl-1,4-phenylenediamine is 1μmol / L-500μmol / L;

[0025] The salt solution is sodium sulfate: 0.1μmol / L~3.5μmol / L or sodium chloride 0.1μmol / L~3.5μmol / L or potassium chloride 0.1μmol / L~3.5μmol / L or potassium chloride (purity ≥97% );

Embodiment 2

[0026] Example 2 Measurement of Imprecision

[0027] The vitamin detector quality control products prepared by the vitamin detector quality control product composition of Example 1 were tested continuously for 10 times with three concentration levels of high, medium and low concentration levels, and the mean, standard deviation and variation were calculated respectively. coefficient, (high concentration: 90-125 μmol / L, medium concentration: 40-85 μmol / L, low concentration: 5-35 μmol / L). Inter-day imprecision determination: The three concentrations of the quality control substances were measured once a day for 20 consecutive days, and the mean, standard deviation and coefficient of variation were calculated. Vitamin detector parameter settings:

[0028] Rest time: 5s

[0029] Enrichment time: 0s

[0030] Enrichment voltage: 0s

[0031] Scanning voltage range: -0.1V-0.7V

[0032] Step voltage: 30mV

[0033] Voltage amplitude: 40mV

[0034] Pulse width: 60mV

[0035] Peri...

Embodiment 3

[0046] Example 3 Stability test

[0047] The quality control material was measured once every working day for 6 consecutive months, and the mean and standard deviation of each month were calculated respectively. The results are shown in Table 4.

[0048] Table 4 Stability test

[0049]

[0050] In conclusion, the different indicators detected all meet the requirements of the quality control product, therefore, the solution of the present invention is completely feasible.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the field of vitamin inspection project quality control, and particularly relates to a vitamin detector quality control product composition and application thereof. The vitamin detector quality control product is prepared from the following components: 2, 3, 5, 6-tetramethyl-1, 4-phenylenediamine and a salt solution. The vitamin detector quality control material composition and the quality control material provided by the invention are stable in chemical property, simple and rapid to operate, small in repeated detection variability, high in accuracy and stability and low in detection cost, the effective period of the quality control material is as long as 12 months, the vitamin detector quality control material composition and the quality control material can be applied to accurate calibration of a vitamin detector, and the stability and reliability of detection data are guaranteed.

Description

technical field [0001] The invention belongs to the field of quality control of vitamin testing items, and in particular relates to a quality control product composition of a vitamin detector and application thereof. Background technique [0002] The human body has little demand for vitamins, and long-term primary or secondary vitamin deficiency will lead to physiological dysfunction of the human body and induce various diseases; on the contrary, excessive intake will easily lead to overload accumulation and even poisoning. The content of vitamins in the body is an effective indicator of nutritional status, and the intake of vitamins is particularly important for pregnant women, infants and young children. As a means of evaluating rational drug use, improving the safety and effectiveness of vitamin use, and realizing individualization of vitamin therapy, vitamin monitoring is gradually being valued by clinical practice. In routine clinical testing, due to the wide distribut...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/416
CPCG01N27/4163
Inventor 秦茂林季忠
Owner 中彦医疗科技有限责任公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com