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An integrated circulation system for the production of nanoporous glass with controllable pore size

A circulatory system and nanoporous technology, applied in the field of material processing devices, can solve problems such as low synthesis efficiency, and achieve the effects of high synthesis efficiency, less waste liquid output, and high solvent utilization rate

Active Publication Date: 2021-10-08
河北迪纳兴科生物科技有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the domestic order cycle of CPG produced by LGC is more than half a year, and there is a phenomenon of low synthesis efficiency

Method used

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  • An integrated circulation system for the production of nanoporous glass with controllable pore size
  • An integrated circulation system for the production of nanoporous glass with controllable pore size
  • An integrated circulation system for the production of nanoporous glass with controllable pore size

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Experimental program
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Effect test

Embodiment 1

[0050] refer to figure 1 , 2 , an integrated circulation system for the production of nanoporous glass with controllable pore size, including

[0051] Reaction components, including a spherical reactor 1;

[0052] Heating assembly, for heating the spherical reactor 1;

[0053] A stirring assembly, comprising a stirrer and a variable frequency motor 32 connected thereto;

[0054] The circulation assembly includes a circulation pump 41 and a water tank, an acid solution tank, an alkali solution tank, and a waste liquid discharge port 42 respectively communicated with the circulation pump 41 through pipelines;

[0055] in:

[0056] The lower discharge end of the spherical reactor 1 is provided with a filter screen, a circulating liquid outlet 14 and a discharge valve 15 in sequence from top to bottom, and its upper end is provided with a feed port 11, a circulating liquid inlet 12 and an agitator inlet; the filter screen is 200-mesh sieve, with an end cover installed on the ...

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PUM

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Abstract

The invention discloses an integrated circulation system for producing nanoporous glass with controllable pore size, which comprises a reaction component; a heating component; a stirring component; a circulation component; The feed port, the upper end of which is provided with a feed port, an agitator inlet and a circulating liquid inlet; the circulating liquid outlet is connected to the circulating pump, and the outlet pipes of the water tank, the acid tank and the alkali tank are connected to the circulating liquid inlet. The preparation process of this system is simple, low energy consumption, less waste liquid output, high solvent utilization rate, and high product production efficiency. What is especially important is that the obtained CPG product has clear channels, no clogging, stable product density, and higher synthesis efficiency. It will have a good application prospect in the direction of oligonucleotide synthesis.

Description

technical field [0001] The invention relates to the field of material processing devices, in particular to an integrated circulation system for producing nanoporous glass with controllable aperture. Background technique [0002] Controlled pore glass (Controlled pore glass) is a carrier material for the synthesis of oligonucleotides, referred to as CPG. Oligonucleotides are fundamental tools for modulating gene expression in biomedical and life science research, and can be developed as gene-targeted therapeutics, which are then used to treat viruses, tumors, and genetic diseases. The 21st century is the century of life science and biotechnology. Domestic biotechnology research has developed rapidly, among which biotechnology such as gene synthesis technology, amplification technology, gene modification technology, gene cloning technology, gene chip technology, and gene therapy technology have already been recognized. Included in the "China High-Tech Development Plan" (863 P...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C03C15/00C03C11/00
CPCC03C11/00C03C15/00
Inventor 卢晋华张阳
Owner 河北迪纳兴科生物科技有限公司