Mixing device for the preparation of pepsinogen recombinant protein and its monoclonal antibody

Abstract

The invention belongs to the technical field of biotechnology, and discloses a mixing device for preparing pepsinogen recombinant protein and its monoclonal antibody. The mixing device for the preparation of pepsinogen recombinant protein and its monoclonal antibody includes a mixing box, the top wall of the mixing box is provided with a material inlet and a cover, and the outer wall of the mixing box is equipped with a constant temperature Jacket, the top of the left wall of the constant temperature jacket and the bottom of the right wall are fixedly connected with water inlet and outlet pipes respectively, and the bottom of the side wall of the mixing tank is fixedly connected with a mounting ring. The mixing device for the preparation of pepsinogen recombinant protein and its monoclonal antibody adopts a circulation pump to provide power to form a circulating mixture. Using the design of the mixing mechanism, the design of the crushing roller and the crushing hole is used to punch the material during the material circulation process. The agglomeration is scattered and re-sprayed into the mixing box to avoid the existence of agglomeration after the mixing is completed, and the material is mixed more fully, which solves the problems raised in the background technology.

Description

technical field [0001] The invention relates to the technical field of biotechnology, in particular to a mixing device for preparing pepsinogen recombinant protein and its monoclonal antibody. Background technique [0002] The preparation of recombinant pepsinogen protein and its monoclonal antibody needs to be uniformly mixed and reacted with the preparation materials. The traditional mixing device usually uses a stirring shaft to stir and mix. However, the preparation material of pepsinogen recombinant protein and its monoclonal antibody It is not only liquid, but also a large amount of powdery materials. After the feeding is completed, due to the existence of air, the contact between the powder and liquid materials will cause agglomeration, especially when some powder materials are not easily soluble in water. Traditional mixing devices are often difficult to solve this problem. The mixed product contains undissolved agglomerates, and the reaction process is not sufficien...

AI Technical Summary

Problems solved by technology

[0002] The preparation of recombinant pepsinogen protein and its monoclonal antibody needs to be uniformly mixed and reacted with the preparation materials. The traditional mixing device usually uses a stirring shaft to stir and mix. However, the preparation material of pepsinogen recombinant protein and its monoclonal antibody It is not only liquid, but also a large amount of powdery materials. After the feeding is completed, due to the existence of air, the contact between the powder and liquid materials will cause agglomeration, especially when some powder materials are not easily soluble in water. Traditional mixing devices are often difficult to solve this problem. The mixed product contains undissolved agglomerates, and the reaction process is insufficient, which affects the quality of the drug and may even cause safety problems.

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