Transdermal delivery skin care gel and preparation method thereof
A skin care gel and gel technology, applied in the field of skin care products, to achieve the effects of improving penetration and utilization, improving product effects, and good biocompatibility
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[0038] The preparation method of the above-mentioned transdermal delivery skin care gel is characterized in that it comprises the following steps:
[0039] The first step is to prepare the skin care active alcohol liposome. The specific process is as follows: 1. Add 50-300 mg of soybean lecithin to 1-3 ml of ethanol, and stir until they dissolve each other to obtain a phospholipid ethanol solution; 2. Add 10-20 components of skin care active drugs into 2-6 ml of aqueous solution and stir to fully dissolve to obtain a skin care active substance solution; 3. Pour the skin care active substance solution in (2) into Put it into the phospholipid ethanol solution in (1), and stir for 30 minutes to make it fully mixed; 4. Ultrasonicate the mixture in (3) at 20-40°C for 5-20 minutes, adjust The pH value is 6.0-7.5, and the skin care active substance alcohol liposome solution can be obtained.
[0040] The second step is to prepare hyaluronic acid gel. The specific process is as follow...
Embodiment 1
[0043] The skin care active substance alcohol liposome is composed of the following substances: 2 milliliters of ethanol, 120 milligrams of soybean lecithin, 10 milligrams of skin care active drug, and 4 milliliters of aqueous solution.
[0044] The hyaluronic acid gel is composed of the following substances: 80 mg of hyaluronic acid substance, 3 ml of aqueous solution.
[0045] The preparation process is as follows:
[0046] The first step, prepare skin care active matter alcohol liposome, specific process is as follows: 1, the soybean lecithin of 120 milligrams is joined in the ethanol of 2 milliliters, and after stirring, until it dissolves mutually, obtains phospholipid ethanol solution; 2, 10 Add milligrams of skin care active drug into 4 ml of aqueous solution and stir to fully dissolve to obtain a skin care active solution; 3. Pour the skin care active solution in (2) into the phospholipid ethanol solution in (1) , stirring for 30 minutes to make it fully mixed; 4. The...
Embodiment 2
[0055] The skin care active substance alcohol liposome is composed of the following substances: 1.5 milliliters of ethanol, 100 milligrams of soybean lecithin, 20 milligrams of skin care active drugs, and 3 milliliters of aqueous solution.
[0056] The hyaluronic acid gel is composed of the following substances: 120 mg of hyaluronic acid substance, 2 ml of aqueous solution.
[0057] The preparation process is as follows:
[0058] The first step, prepare skin care active matter alcohol liposome, specific process is as follows: 1, the soybean lecithin of 100 milligrams is joined in the ethanol of 1.5 milliliters, and after stirring, until it dissolves mutually, obtains phospholipid ethanol solution; 2, 20 Add milligrams of skin care active drug into 3 ml of aqueous solution and stir to fully dissolve to obtain skin care active substance solution; 3. Pour the skin care active substance solution in (2) into the phospholipid ethanol solution in (1) , stirring for 30 minutes to mak...
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