High-strength bioactive interbody fusion cage and manufacturing method thereof
An intervertebral fusion device and bioactive technology, applied in the field of high-strength bioactive intervertebral fusion device and its manufacturing, can solve problems such as delayed inflammatory response, poor biocompatibility of fusion device materials, and collapse of intervertebral space, achieving Promotes bone regeneration and repair, is not easy to wear, and is easy to operate
Pending Publication Date: 2021-03-09
HANGZHOU DIANZI UNIV
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Problems solved by technology
However, there are still many deficiencies in the current fusion cages, such as poor biocompatibility of fusion cage materials, collapse of the intervertebral space, delayed inflammatory response, etc.
Method used
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Embodiment 1
[0053] The manufacturing method of intervertebral fusion cage with anti-tumor, osteogenic and pro-vascularization functions for lumbar interbody fusion is as follows:
[0054] 1) Choose titanium alloy as the material of the middle layer, silica gel as the material of the outer layer, calcium magnesium silicate with a magnesium content of 1.6% as the inner layer material A, calcium silicate material containing strontium as the inner layer material B, containing copper The calcium silicate material is used as the inner layer material C, and the calcium silicate material with antineoplastic drugs is used as the inner layer material D;
[0055] 2) According to the mechanical properties required by the intervertebral fusion cage and the material properties of the titanium alloy, the outline of the titanium alloy intermediate layer is designed. The internal porosity is 30%, the pore diameter is 100 microns, the pore structure is grid type, and there are The two units are respectivel...
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Abstract
The invention discloses a high-strength bioactive interbody fusion cage and a manufacturing method thereof. The interbody fusion cage is composed of an outer layer, a middle layer and an inner layer,wherein the middle layer is wrapped in the outer layer, and the inner layer is installed in the middle layer; the outer layer is made of soft materials; the middle layer is of a porous structure, andinternal pore channels are completely through; and the inner layer is a combination of two or more bioactive materials of a porous structure, internal pore channels are completely through, and the inner layer can be a combination of calcium magnesium silicate, silicate or phosphate or a combination of bioactive materials with some special functions. The middle layer comprises an inlet and a rail,the inner layer enters the middle layer through the inlet, and the inner layer is movably installed on the rail. The high-strength bioactive interbody fusion cage has high mechanical strength, good position stability and good bioactivity, and meanwhile multiple functions can be added.
Description
technical field [0001] The invention relates to a device in the technical field of medical devices and a manufacturing method thereof, in particular to a high-strength bioactive intervertebral fusion device and a manufacturing method thereof. Background technique [0002] With the aging of the population, spinal degenerative diseases with neck and shoulder pain and low back pain as the main symptoms are seriously affecting people's work and life. Intervertebral body fusion is one of the main methods for the treatment of spinal degenerative diseases. Through the unremitting efforts of researchers, different types of intervertebral fusion devices have been developed one after another and gradually applied in clinical practice. An ideal intervertebral fusion device needs to be able to correct spinal deformity, restore normal physiological curvature, maintain the stability of the intervertebral space, and most importantly, promote bone fusion. However, there are still many def...
Claims
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IPC IPC(8): A61F2/44A61F2/30A61L27/02A61L27/06A61L27/50A61L27/54A61L27/56A61L27/58
CPCA61F2/4455A61F2/30771A61F2/30942A61L27/06A61L27/025A61L27/56A61L27/50A61L27/54A61L27/58A61F2002/30329A61F2002/30784A61F2002/30985A61F2002/3097A61L2430/38A61L2300/416A61L2300/412A61L2300/604
Inventor 邵惠锋景卓荦贺永年志恒龚友平刘海强陈慧鹏李文欣
Owner HANGZHOU DIANZI UNIV