Bioactive interbody fusion cage and manufacturing method thereof
An intervertebral cage, a bioactive technology, applied in the field of bioactive intervertebral cages and their manufacturing, can solve the problems of intervertebral space collapse, delayed inflammatory response, and biocompatibility of cage materials, etc. The effect of promoting bone regeneration and repair, convenient operation and low manufacturing cost
Active Publication Date: 2021-04-06
HANGZHOU DIANZI UNIV
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Problems solved by technology
However, there are still many deficiencies in the current fusion device, including the biocompatibility of the fusion device material, the collapse of the intervertebral space, and the delayed inflammatory response.
Method used
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Embodiment 1
[0054] The manufacturing method of the intervertebral cage for lumbar interbody fusion is as follows:
[0055] 1) Titanium alloy is selected as the material of the middle layer, silica gel is used as the material of the outer layer, and calcium magnesium silicate with a magnesium content of 1.6% is used as the material of the inner layer;
[0056] 2) According to the mechanical properties required by the intervertebral fusion cage and the material properties of the titanium alloy, the outline of the titanium alloy intermediate layer is designed. The internal porosity is 30%, the pore diameter is 100 microns, the pore structure is grid type, and there are The two units are respectively arranged on the top and bottom of the middle layer, the shape of the entrance is triangular, and the cross-sectional shape of the track is V-shaped, and then the designed middle layer structure model is imported into the metal 3D printing equipment, through the selective laser melting process The...
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Abstract
The invention discloses a bioactive interbody fusion cage and a manufacturing method thereof. The interbody fusion cage comprises an outer layer, a middle layer wrapped in the outer layer and an inner layer installed in the middle layer. The outer layer is made of a soft material, can be hydrogel, and can also be silica gel and the like; the middle layer is of a porous structure, internal pore channels are completely communicated, and the middle layer can be titanium alloy or PEEK and the like. The inner layer is made of a bioactive ceramic material with a porous structure, and internal pore passages are completely communicated and calcium magnesium silicate, silicate, phosphate or the like can be selected. The middle layer comprises an inlet and a rail, the inner layer enters the middle layer through the inlet, and the inner layer is movably installed on the rail. The bioactive interbody fusion cage provided by the invention has high mechanical strength, good position stability and good biological activity.
Description
technical field [0001] The invention relates to a device in the technical field of medical devices and a manufacturing method thereof, in particular to a bioactive intervertebral fusion device and a manufacturing method thereof. Background technique [0002] With the aging of the population, spinal degenerative diseases with neck and shoulder pain and low back pain as the main symptoms are seriously affecting people's work and life. Intervertebral body fusion is one of the main methods for the treatment of spinal degenerative diseases. Since Kuslich et al. used intervertebral fusion for lumbar interbody fusion for the first time in 1988, intervertebral fusions of various materials have come out one after another and have been gradually applied in clinic. [0003] Through the unremitting efforts of scientific researchers, different types of intervertebral fusion devices have been developed and gradually applied in clinical practice. An ideal intervertebral fusion device nee...
Claims
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IPC IPC(8): A61F2/30A61F2/44A61L27/02A61L27/10A61L27/12A61L27/54A61L27/56
CPCA61F2/4455A61F2/30771A61F2/30942A61L27/54A61L27/10A61L27/12A61L27/025A61L27/56A61F2002/30329A61F2002/30784A61F2002/30985A61F2002/3097A61L2430/38A61L2300/112A61L2300/102A61L2300/412Y02P10/25
Inventor 邵惠锋景卓荦贺永年志恒龚友平刘海强陈慧鹏李文欣
Owner HANGZHOU DIANZI UNIV