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Membrane emulsification device capable of being quickly disassembled and assembled and application of device

A technology of membrane emulsification and membrane emulsifier, applied to chemical instruments and methods, laboratory containers, laboratory utensils, etc., can solve the problems of inconvenient disassembly and installation, difficult cleaning, uneven particle size distribution, etc., to achieve Ease of maintenance and cleaning

Pending Publication Date: 2021-09-17
山东采采医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, most microsphere research is still in the laboratory stage, and there are still many problems and restrictions if it is to be put into clinical practice.
At present, it is inconvenient to disassemble and install the membrane emulsification device in the laboratory stage, and it is difficult to clean; and there are large differences in the particle size of the microspheres, and the problem of uneven particle size distribution

Method used

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  • Membrane emulsification device capable of being quickly disassembled and assembled and application of device
  • Membrane emulsification device capable of being quickly disassembled and assembled and application of device
  • Membrane emulsification device capable of being quickly disassembled and assembled and application of device

Examples

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Effect test

Embodiment 1

[0036] Such as figure 1 and figure 2 As shown, this embodiment proposes a membrane emulsification device that can be quickly disassembled, including a membrane emulsifier, and the structure of the membrane emulsifier is as follows figure 1 As shown, the structure of the membrane emulsifier includes a stainless steel membrane emulsifier housing 7, the membrane emulsifier housing 7 includes an outer tube 1 and an inner tube 2, the inner tube 2 passes through the outer tube 1, and the two are parallel Standing; two ends of the inner membrane tube 2 are provided with two horizontal inlets and outlets, which are respectively horizontal inlets and outlets I3 and horizontal inlets and outlets II4; The diameters of the pipe 2, the side inlet and outlet I5 and the side inlet and outlet II6 are both 3 cm. The side inlet and outlet I5 are located at the upper end, and the side inlet and outlet II6 are located at the lower end. Both the side inlet and outlet II6 are provided with a con...

Embodiment 2

[0043] Such as Figure 5As shown, the present embodiment proposes a microsphere preparation device, comprising a continuous phase tank, a dispersed phase tank, an emulsification tank 18, a filter 19 and a waste liquid collection device 20, the continuous phase adopts water, the dispersed phase adopts oil, and the emulsification tank 18 It is connected with the filter 19 through a detachable pipeline, and the waste liquid collection device 20 is connected under the filter 19, and also includes a quick-dismountable membrane emulsification device 16 described in Embodiment 1, which can be quickly disassembled and assembled for emulsification The device 16 is detachably connected with the continuous phase tank 15 and the dispersed phase tank 17 respectively, and the detachable membrane emulsification device 16 is detachably connected with the emulsification tank 18;

[0044] The specific connection relationship between the membrane emulsification device 16 and the continuous phase...

Embodiment 3

[0052] This embodiment proposes a microsphere preparation device, which is different from the microsphere preparation device proposed in Example 2. The microsphere preparation device proposed in this embodiment adopts two quickly detachable membrane emulsification devices 16 to be connected in series, respectively Membrane emulsifier I23 and membrane emulsifier II24, the structure of membrane emulsifier I23 and the membrane emulsifier described in Embodiment 1 are exactly the same, its horizontal inlet and outlet are respectively horizontal inlet and outlet III25 and horizontal inlet and outlet IV26, and its side inlets and outlets are respectively side inlet and outlet III27 and the side inlet and outlet IV28; the micropore diameter of the inner membrane tube of the membrane emulsifier II24 is 50 μm, and all the other structures are the same as the structure of the membrane emulsifier described in Example 1, and the horizontal inlets and outlets are respectively horizontal inle...

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Abstract

The invention relates to the technical field of microsphere preparation, in particular to a membrane emulsification device capable of being rapidly disassembled and assembled and application of the device. The membrane emulsification device capable of being rapidly disassembled and assembled comprises a membrane emulsifier, a connecting piece, an annular clamp and a baffle plate, the membrane emulsifier comprises a membrane emulsifier shell, an outer layer pipe and an inner membrane pipe are arranged in the membrane emulsifier shell, two horizontal inlets and outlets are formed in the two ends of the inner membrane pipe, two side inlets and outlets are formed in the side wall of the outer layer pipe, a pipe opening part of the inner membrane pipe protrudes out of the membrane emulsifier shell, the protruding part of the inner membrane pipe is a clamping part, and protruding parts are arranged at the two ends of the membrane emulsifier shell; and the connecting piece comprises an inner connecting pipe and a connecting piece shell, the inner connecting pipe is recessed in the connecting piece shell, and a clamping groove is formed in the recessed position. The membrane emulsification device is simple in structure and reasonable in design, all the devices can be detachably connected, and maintenance and cleaning are convenient; and meanwhile, multi-stage series connection can be carried out according to actual requirements of an experiment, and various particle sizes meeting the requirements of the experiment can be prepared at the same time.

Description

technical field [0001] The invention relates to the technical field of microsphere preparation, in particular to a quickly detachable membrane emulsification device and its application. Background technique [0002] The membrane emulsification method is to give a certain pressure to the dispersed phase, so that it passes through a membrane tube with uniform pores to form small uniform droplets into the continuous phase, and the continuous phase takes the dispersed phase droplets out of the membrane at a certain flow rate for emulsification The device completes the membrane emulsification process, and the membrane emulsifier plays an important role in this process. [0003] At this stage, most microsphere research is still in the laboratory stage, and there are still many problems and restrictions if it is to be put into clinical practice. At present, the membrane emulsification device in the laboratory stage is inconvenient to disassemble and install, and it is difficult to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01J13/12B01L3/00
CPCB01J13/125B01L3/502769
Inventor 陈儒浩秦昌张娜苏义强
Owner 山东采采医疗科技有限公司