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Identification and quantification of the degree of tissue hypoxia

A technique of organization and degree applied in the field of corresponding computer program products

Pending Publication Date: 2021-12-03
OBI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, these methods for describing signs of tissue hypoxia have various limitations, such as being influenced by other medical conditions

Method used

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  • Identification and quantification of the degree of tissue hypoxia
  • Identification and quantification of the degree of tissue hypoxia
  • Identification and quantification of the degree of tissue hypoxia

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Embodiment Construction

[0094] The present invention is a method and corresponding computer system for identifying the extent to which tissue hypoxia has modified measures of arterial acid-base chemistry. Elements of the invention are comparisons of calculated and measured values ​​of acid-base chemistry.

[0095] figure 2 is a schematic diagram of the method of the present invention. The method illustrated on this figure includes: inputs from a previous method using designated and unspecified venous blood samples to obtain "calculated arterial" values ​​for acid-base and oxygenation status (see WO2004 / 010861 of OBI Medical Aps , Denmark)) (5), as defined in steps a, b and c of the first aspect of the invention. In this context, the term "non-specific" venous blood is used to denote a venous sample, where no understanding is made as to whether the sample has been modified by mechanisms other than aerobic metabolism during its transit through tissue. Therefore, it is not known whether this sample ...

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Abstract

The present invention relates to a method for identification of tissue hypoxia from measurements of acid-base and oxygenation status from venous and / or arterial blood.

Description

technical field [0001] The present invention relates to a computer-implemented method for identifying the degree of tissue hypoxia. This method analyzes the difference between arterial and venous oxygenation and acid-base status and isolates the components of this difference due to tissue hypoxia. The invention also relates to a corresponding data processing system, and a corresponding computer program product for execution on a computer. Background technique [0002] Patients with critical illness often present with circulatory or metabolic disturbances that lead to tissue hypoxia. This in turn may lead to the production of strong acid in the tissues and the transport of this strong acid into the blood. Furthermore, this may lead to a buffering of these strong acids in the tissues, which raises the partial pressure of carbon dioxide (PCO 2 ), and leads to a CO 2 Transport from tissue to blood, which exceeds that due to normal aerobic metabolism. strong acid and excess ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/145A61M16/00
CPCA61B5/14542G16H50/20A61B5/412
Inventor B·格拉弗森L·莎斯特里L·P·汤姆森S·E·里斯
Owner OBI
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