Antibacterial coating with phosphatase response function, functional material with antibacterial coating and preparation method of functional material
A technology of antibacterial coatings and functional materials, applied in coatings, antifouling/underwater coatings, chemical instruments and methods, etc., can solve the problems of reducing the sterilization effect, improve hydrophilicity, easy operation, prevent bacteria and The effect of pollutant adhesion
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
preparation example Construction
[0165] The present invention also provides a method for preparing a functional material with an antibacterial coating described in any one of the above technical solutions, characterized in that it comprises the following steps:
[0166] 1) will have R 1 The hydroxybenzophenone derivative monomer with the H structure, the pH regulator, the catalyst and the epoxyhaloalkane having the structure of formula (III) are mixed and reacted, and the first intermediate is obtained after precipitation;
[0167]
[0168] Wherein, X is selected from Cl, Br or I;
[0169] 2) reacting the first intermediate obtained in the above steps, the monomer having the structure of formula (IV), the pH adjustment solution and the first solvent again to obtain the second intermediate;
[0170]
[0171] 3) After continuing to react the second intermediate, phosphorus trichloride, organic base and second solvent obtained in the above steps, a zwitterionic polymer having a structure shown in formula ...
Embodiment 1
[0280] a. Mix 4g of 3-hydroxymethylbenzophenone, 5.2g of potassium carbonate, 0.3g of tetrabutylammonium bromide and 9.25g of epichlorohydrin in a flask and react in an oil bath at 110°C for 24h. After the reaction The product of the product was diluted with 100mL ethyl acetate, and the product was extracted three times with 50mL saturated brine, the organic phase was collected and dried with anhydrous sodium sulfate, and the solvent was spin-dried by a rotary evaporator to obtain a yellow oily product;
[0281] b. 3 g of the product of step a and 6.42 g of N,N-dimethylhexylamine were dissolved in 50 mL of methanol, and 2.5 mL of hydrochloric acid-dioxane solution with a concentration of 2 mol / L was added dropwise to the solution, and reacted at 80°C for 9 hours The product was evaporated to dryness by rotary evaporation, and the product was purified with a chromatographic silica gel column, and the purified product was collected;
[0282] c. The product of step b is dissolved...
Embodiment 2
[0286] a. Dissolve 3.8 g of 3-bromobenzophenone and 2.5 g of N-ethylethanolamine in 50 mL of dimethyl sulfoxide solution, and heat at 80° C. for 12 h. Then use 200mL of n-hexane to precipitate the product, then wash the product with 50mL of n-hexane for 3 times and then dry it in vacuum for 12h;
[0287] b. Dissolve 3.5 g of the product in step a and 6.8 g of bromododecane in 70 mL of dimethyl sulfoxide, and react at 60° C. for 8 h. Precipitate the product with 300mL ether, wash with 50mL ether several times after centrifugation, and dry in vacuum for 12h.
[0288] c. Dissolve 3 g of the product of step b in 70 mL of methanol, add dropwise 0.022 mL of phosphorus trichloride and 0.05 mL of pyridine, react at room temperature for 5 h, and remove the solvent by rotary evaporation, wash the product with saturated saline, and finally use a chromatographic silica gel column to Product purification.
[0289] d. Dissolve 1 g of the zwitterionic small molecule prepared in step c in a...
PUM
| Property | Measurement | Unit |
|---|---|---|
| thickness | aaaaa | aaaaa |
| wavelength | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
Login to View More