A multi-index detection device and its multi-index detection chip and using method
A detection chip, multi-index technology, applied in the direction of chemical instruments and methods, biochemical cleaning devices, biochemical equipment and methods, etc., can solve the problems of complex, expensive hardware systems, and incompatible with rapid detection.
Active Publication Date: 2022-07-05
CAPITALBIO CORP +1
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However, existing microfluidic chips for multi-index nucleic acid detection generally require more complex fluid control hardware, such as syringe pumps, centrifugal motors, etc. to drive the fluid on the chip, resulting in a more complex and expensive hardware system, which is not suitable for on-site rapid testing needs
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[0042] One of the cores of the present invention is to provide a multi-indicator detection chip. The structure of the multi-indicator detection chip is designed to reduce the demand for supporting hardware in the multi-indicator detection process, reduce the use cost, improve portability, and meet the needs of multi-indicator fast detection. detection needs.
[0043] Another core of the present invention is to provide a multi-index detection device based on the above-mentioned multi-index detection chip and a method of using the same.
[0044] The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary ski...
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The invention relates to a multi-index detection device, a multi-index detection chip and a method of using the same. The multi-index detection chip includes a chip body, the chip body is provided with a plurality of reaction units, and the reaction units include a sample liquid storage cavity, a sealed body cavity, and a reaction cavity. and a sample pipeline, the reaction chamber and the sample pipeline are respectively connected with the sample liquid storage cavity in the downstream direction of the sample liquid storage cavity along the sample flow direction, the sample pipeline is used to connect the sample liquid storage cavity of two adjacent reaction units, and the sealed body cavity is used for The sealing body is contained and the sealing body cavity is communicated with the sample pipeline; the sample liquid storage cavities of each reaction unit are connected in series through the sample pipeline in turn, and the two sample liquid storage cavities located at both ends are respectively connected to the sample inlet and the sample outlet; the above-mentioned multi-index detection The chip can realize the driving of the sample liquid without the aid of fluid manipulation hardware, thereby reducing the demand for supporting hardware in the detection process, reducing the use cost, improving portability, and meeting the needs of rapid detection.
Description
technical field [0001] The invention relates to the field of in vitro diagnosis and the technical field of microfluidics, in particular to a multi-index detection device, a multi-index detection chip and a use method thereof. Background technique [0002] Microfluidic chip is a technology that has developed rapidly in recent years. It is characterized by low sample consumption, high degree of automation, high throughput and easy integration. It is widely used in the fields of biochemical testing, immunoassay, environmental monitoring and food safety testing. . [0003] When the epidemic breaks out, there will be a large number of nucleic acid testing needs, including batch testing suitable for central laboratories, and on-site rapid testing. On-site rapid detection has very high requirements on the portability of the detection system, and also has high requirements on the cost of related devices. The multi-index nucleic acid detection technology based on microfluidic chips...
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IPC IPC(8): C12M1/34C12M1/02C12M1/00B01L3/00C12Q1/6844
CPCB01L3/5027B01L3/50273C12Q1/6844C12Q2531/119C12Q2527/101C12Q2565/629
Inventor 刘冬辰王旭徐友春程京
Owner CAPITALBIO CORP