Traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection and preparation method thereof

Abstract

A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection and its preparation method include the following raw materials in parts by weight: 20-40 parts of cactus, 20-40 parts of houttuynia cordata root, 10-20 parts of honeysuckle vine, 10-20 parts of trachelospermum jasminoides vine, 5-15 parts of sophora flavescens, 5-15 parts of kochia scoparia fruit, 5-15 parts of dictamnus dasycarpus root bark, 5-15 parts of artemisia capillaris, 8-12 parts of polygonum cuspidatum, 4-8 parts of atractylodes lancea, 8-15 parts of poria cocos, 5-15 parts of cynanchum paniculatum, and 8-12 parts of peony root. The measured granules of honeysuckle vine, trachelospermum jasminoides vine, sophora flavescens, kochia scoparia fruit, dictamnus dasycarpus root bark, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, poria cocos, cynanchum paniculatum, and peony root are added to hot water and stirred until evenly dispersed to obtain a viscous medicinal liquid. Fresh cactus and houttuynia cordata root are washed, the thorns of the cactus are removed, both are mashed and filtered, and the filtrate is evenly mixed with the viscous medicinal liquid to obtain the aforementioned traditional Chinese medicine dressing. The traditional Chinese medicine formula of this invention has a good therapeutic effect on cellulitis caused by progesterone injection, with a cure rate of up to 98%, and no discomfort or side effects, and can be widely used.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine dressings, and in particular to a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injections and its preparation method. Background Technology

[0002] In clinical practice, many women undergoing assisted reproductive technology or experiencing recurrent miscarriages often receive intramuscular progesterone injections in the buttocks before 12 weeks of pregnancy. This medication has a high viscosity, and prolonged intramuscular injection can easily cause local subcutaneous soft tissue induration and poor local circulation. Even after the patient stops intramuscular progesterone injections at 12 weeks, the induration at the injection site may persist for a long time. A small number of patients who are bedridden for extended periods during the mid-to-late stages of pregnancy experience further poor local circulation due to prolonged pressure at the original progesterone injection site. Combined with decreased resistance, this can lead to redness, swelling, heat, and pain at the injection site, i.e., cellulitis. If cellulitis is not treated promptly, the inflammation can spread to surrounding areas, eventually forming an abscess.

[0003] For cellulitis, Western medicine generally uses antibiotics, such as penicillin, cefoperazone, clarithromycin, and sulfamethoxazole. However, due to safety concerns regarding medication use in pregnant women, and especially since the babies are often precious, many Western doctors and patients themselves are hesitant to use these medications. Therefore, traditional Chinese medicine has become a better option. Summary of the Invention

[0004] The purpose of this invention is to overcome the shortcomings of the prior art and provide a traditional Chinese medicine dressing with good efficacy and no side effects for treating cellulitis caused by progesterone injection, as well as a method for preparing the traditional Chinese medicine dressing.

[0005] This invention is achieved through the following technical solution: A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection comprises the following raw materials in parts by weight: 20-40 parts of cactus, 20-40 parts of houttuynia cordata root, 10-20 parts of honeysuckle vine, 10-20 parts of trachelospermum jasminoides vine, 5-15 parts of sophora flavescens, 5-15 parts of kochia scoparia fruit, 5-15 parts of dictamnus dasycarpus root bark, 5-15 parts of artemisia capillaris, 8-12 parts of polygonum cuspidatum, 4-8 parts of atractylodes lancea, 8-15 parts of poria cocos, 5-15 parts of cynanchum paniculatum, and 8-12 parts of peony root.

[0006] Further optimized, the ingredients include the following parts by weight: 30 parts cactus, 30 parts houttuynia cordata root, 15 parts honeysuckle vine, 15 parts trachelospermum jasminoides vine, 10 parts sophora flavescens, 10 parts kochia scoparia fruit, 10 parts dictamnus dasycarpus root bark, 10 parts artemisia capillaris, 10 parts polygonum cuspidatum, 6 parts atractylodes lancea, 10 parts poria cocos, 10 parts cynanchum paniculatum, and 10 parts peony root.

[0007] In a further optimized manner, the cactus is the fresh stem material after the thorns and skin have been removed.

[0008] Furthermore, the houttuynia cordata root is a fresh medicinal material.

[0009] In this herbal dressing formula, fresh cactus and houttuynia cordata have the effects of clearing heat and detoxifying, reducing inflammation and relieving pain, and together they are the principal herbs. Honeysuckle vine and trachelospermum jasminoides are added to clear heat and cool the blood, dispel wind and unblock the meridians, and together they are the assistant herbs. These herbs not only strengthen the heat-clearing and detoxifying effects of the principal herbs, but also dispel wind and unblock the meridians, which helps improve local microcirculation, aids in the absorption of inflammation, and removes heat toxins. The formula is supplemented with herbs such as sophora flavescens, kochia scoparia, dictamnus dasycarpus, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, and poria cocos to clear heat and resolve dampness, while cynanchum paniculatum and peony root can invigorate blood and remove blood stasis. The entire formula works synergistically to clear heat and detoxify, resolve dampness and unblock the meridians.

[0010] Specifically, cactus has the effects of clearing heat and detoxifying, reducing swelling and relieving pain. External application can treat sores and boils. The triterpenoids in cactus have anti-inflammatory and analgesic effects, which can relieve bruises and joint pain. Houttuynia cordata has the effects of clearing heat and detoxifying, antibacterial and antiviral, enhancing immunity, and reducing allergic reactions. Lonicera japonica has the effects of clearing heat and detoxifying, dispelling wind and unblocking meridians, cooling blood and reducing swelling. Trachelospermum jasminoides has the effects of dispelling wind and unblocking meridians, cooling blood and reducing swelling. Sophora flavescens has the effects of clearing heat, antibacterial, balancing oil, shrinking pores, and repairing damaged skin, and can relieve allergic reactions. Kochia scoparia has the effects of clearing heat and removing dampness, relieving skin itching, antibacterial and anti-inflammatory, and reducing skin inflammation. Dictamnus dasycarpus can inhibit bacteria and viruses, reduce inflammatory reactions, and clear dampness. Heat-relieving and soothing effects include relieving skin itching and allergic reactions; Artemisia capillaris has antibacterial and anti-inflammatory properties, inhibits bacterial growth, and reduces inflammatory reactions; Polygonum cuspidatum has antibacterial (inhibits bacterial growth), anti-inflammatory (reduces inflammatory reactions), and antioxidant (scavenges free radicals) effects, and can reduce swelling and relieve pain; Atractylodes lancea, when used externally, can relieve skin dampness and turbidity, dispel wind and cold, and can help reduce inflammatory reactions and relieve pain; Poria cocos, when used externally, has the effects of removing dampness and relieving itching, and promoting skin repair, and is often used to relieve eczema, skin inflammation, minor injuries, and other problems, and can promote wound healing; Cynanchum paniculatum, when used externally, mainly has the effects of dispelling wind and dampness, relieving itching and pain, detoxifying and reducing swelling, promoting blood circulation and removing blood stasis, and antibacterial and anti-inflammatory effects; Paeonia lactiflora, when used externally, has the effects of clearing heat and cooling blood, dispersing blood stasis and relieving pain, reducing swelling and antibacterial effects.

[0011] A method for preparing a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection includes the following steps: S1. Add the measured honeysuckle vine, trachelospermum jasminoides, sophora flavescens, kochia scoparia, dictamnus dasycarpus, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, poria cocos, cynanchum paniculatum, and paeonia lactiflora to water and decoct for 30-60 minutes. After filtering out the residue, continue to decoct over low heat until the liquid is concentrated into a viscous liquid. S2. Fresh cactus and houttuynia cordata roots are washed, the thorns of the cactus are removed, both are mashed and filtered, and the filtrate is evenly mixed with the viscous medicinal liquid obtained in step S1 to obtain the Chinese herbal dressing.

[0012] Further optimized, the following ingredients are used: 15g of Lonicera japonica vine, 15g of Trachelospermum jasminoides vine, 10g of Sophora flavescens root, 10g of Kochia scoparia fruit, 10g of Dictamnus dasycarpus root bark, 10g of Artemisia capillaris, 10g of Polygonum cuspidatum root, 6g of Atractylodes lancea rhizome, 10g of Poria cocos, 10g of Cynanchum paniculatum root, 10g of Paeonia lactiflora root, 800mL of water, 50mL of the final concentrated viscous medicinal liquid, 30g of prickly pear cactus (after removing thorns), and 30g of Houttuynia cordata root.

[0013] A method for preparing a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection includes the following steps: S1. Add the measured amount of honeysuckle vine, star jasmine vine, sophora flavescens, kochia scoparia fruit, dictamnus dasycarpus root bark, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, poria cocos, cynanchum paniculatum, and red peony root to hot water and stir to disperse evenly to obtain a viscous medicinal liquid. S2. Fresh cactus and houttuynia cordata roots are washed, the thorns of the cactus are removed, both are mashed and filtered, and the filtrate is evenly mixed with the viscous medicinal liquid obtained in step S1 to obtain the Chinese herbal dressing.

[0014] Based on traditional folk remedies, this invention uses fresh cactus and houttuynia cordata root as the principal ingredients, and adds honeysuckle vine and trachelospermum jasminoides as the assistant ingredients, along with other traditional Chinese herbs such as sophora flavescens, kochia scoparia, dictamnus dasycarpus, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, and poria cocos, to prepare a topical Chinese medicine dressing. This dressing is then combined with a modern mid-frequency transdermal drug delivery device for local transdermal treatment. Clinical practice has shown that it has a good therapeutic effect on cellulitis caused by progesterone injections, with a cure rate of up to 98%, and no discomfort or side effects. It is suitable for widespread application. Detailed Implementation

[0015] A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection comprises the following raw materials in parts by weight: 20-40 parts of cactus, 20-40 parts of houttuynia cordata root, 10-20 parts of honeysuckle vine, 10-20 parts of trachelospermum jasminoides vine, 5-15 parts of sophora flavescens, 5-15 parts of kochia scoparia fruit, 5-15 parts of dictamnus dasycarpus root bark, 5-15 parts of artemisia capillaris, 8-12 parts of polygonum cuspidatum, 4-8 parts of atractylodes lancea, 8-15 parts of poria cocos, 5-15 parts of cynanchum paniculatum, and 8-12 parts of peony root.

[0016] Example 1 A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection comprises the following raw materials in parts by weight: 30 parts cactus, 30 parts houttuynia cordata root, 15 parts honeysuckle vine, 15 parts trachelospermum jasminoides vine, 10 parts sophora flavescens, 10 parts kochia scoparia fruit, 10 parts dictamnus dasycarpus root bark, 10 parts artemisia capillaris, 10 parts polygonum cuspidatum, 6 parts atractylodes lancea, 10 parts poria cocos, 10 parts cynanchum paniculatum, and 10 parts paeonia lactiflora. The cactus is the fresh stem after removing thorns and peeling, the houttuynia cordata root is fresh, and the rest are processed medicinal materials.

[0017] The preparation method of the above-mentioned traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection includes the following steps: S1. Add 15g of honeysuckle vine, 15g of star jasmine vine, 10g of sophora flavescens, 10g of kochia scoparia fruit, 10g of dictamnus dasycarpus root bark, 10g of artemisia capillaris, 10g of polygonum cuspidatum, 6g of atractylodes lancea, 10g of poria cocos, 10g of cynanchum paniculatum, and 10g of peony root to 800mL of filtered tap water and decoct for 40 minutes. After filtering the residue, continue to simmer the decoction over low heat until it is concentrated to 50mL of viscous liquid. S2. Fresh herbs, including 30g of cactus and 30g of houttuynia cordata root, are washed and cleaned. The thorns of the cactus are removed. Both herbs are added to a pulping machine and mashed for 5 minutes. The mixture is then filtered. The filtrate is mixed evenly with the viscous medicinal liquid obtained in step S1 to obtain the Chinese herbal dressing. The dressing is then poured into a sterilized small container for later use.

[0018] Example 2 The rest is the same as in Example 1, except that in step S1, 15g of honeysuckle vine, 15g of star anise vine, 10g of sophora flavescens, 10g of kochia scoparia fruit, 10g of dictamnus dasycarpus root bark, 10g of artemisia capillaris, 10g of polygonum cuspidatum, 6g of atractylodes lancea, 10g of poria cocos, 10g of cynanchum paniculatum, and 10g of peony root are all made from traditional Chinese medicine granules. These granules are added to 40ml of boiling water and stirred evenly to obtain a viscous medicinal liquid. Then, they are mixed with cactus and houttuynia cordata to obtain a traditional Chinese medicine dressing, which is poured into a sterilized small container for later use.

[0019] Example 3 Prepare two sterile medical gauze pads. Use sterile tweezers to place the gauze pads into the small container containing the Chinese medicine dressing as described in Example 1 or Example 2, and let the entire gauze pad be soaked in the medicine solution.

[0020] Disinfect the electrode plates of the intermediate frequency drug penetration therapy device and the patient's affected skin with 75% alcohol or povidone-iodine. Use sterile tweezers to remove the gauze soaked in the drug solution and lay it flat on the patient's buttocks.

[0021] Place the inner sides of the two electrode plates on top of the gauze block and secure them slightly with medical tape. Turn on the switch of the medium-frequency drug transdermal therapy device, select a temperature of 40-50 degrees Celsius, and a duration of 30 minutes.

[0022] For cases where pus has formed (the affected skin feels fluctuant to the touch), after the medication has penetrated, combine it with bloodletting and cupping. The specific procedure is as follows: (1) Put on medical gloves and disinfect the affected skin again; (2) Use a No. 7 needle to prick the pus-forming area 3-4 times to a depth of 2-3 mm, and then apply cupping; (3) Leave the container in the container for 10 minutes; (4) After removing the jar, clean the bloodstains with a sterile cotton ball and disinfect and cover the dressing again.

[0023] The above treatments can be administered 3-7 times until a full recovery is achieved.

[0024] The herbal dressing formula of this invention is inspired by the traditional Chinese folk remedy of applying crushed cactus or houttuynia cordata externally to treat boils and carbuncles. Fresh cactus and houttuynia cordata roots are taken and mixed with traditional Chinese herbs for clearing heat and detoxifying, removing dampness and unblocking meridians to prepare a medicinal liquid. Combined with a modern medium-frequency drug penetration therapy device for local drug penetration therapy, the therapeutic effect was found to be very good, and no discomfort or side effects were found in patients. Therefore, the treatment was spread to patients who came for treatment.

[0025] Clinical evidence shows that in the past five years, the TCM clinic has treated 50-80 patients annually with cellulitis caused by progesterone injection sites. Many of these patients were already in the purulent stage. After 2-8 treatments, the vast majority of them were cured, with a cure rate of about 98%.

[0026] Here are two clinical cases: Case 1: Mr. Deng, outpatient medical record number: 2212****, date of visit: November 12, 2025.

[0027] Chief complaint: Redness, swelling, heat and pain at the site of intramuscular progesterone injection on both buttocks for 10 days.

[0028] Present Illness: In August, the patient underwent IVF-ET at our hospital and successfully conceived. Afterward, the patient received intramuscular progesterone injections outside the hospital for two months to maintain the pregnancy. Ten days ago, after eating fried food, the patient began to experience redness, swelling, heat, and pain at the site of the intramuscular progesterone injection on both buttocks, causing restlessness. The patient visited a local clinic (details unknown) and was given oral cefixime capsules for three days without relief. The patient then came to our department for treatment.

[0029] Physical examination: Redness and swelling of the skin on both sides of the buttocks in an area about 8cm in diameter, increased skin temperature upon touch, accompanied by significant pain, and obvious fluctuation upon palpation of the center.

[0030] Tongue and pulse characteristics: red tongue with yellow and greasy coating, and slippery pulse.

[0031] Diagnosis: Cellulitis of the buttock (phlegm-heat accumulation).

[0032] Treatment: Clear heat and detoxify, resolve dampness and drain pus.

[0033] Prescription: Two applications of localized herbal medicine solution (once a day), and two applications of local bloodletting and cupping (once every other day).

[0034] Chinese herbal formula (by weight): 30 parts fresh cactus, 30 parts fresh houttuynia cordata root, 15 parts honeysuckle vine, 15 parts trachelospermum jasminoides vine, 10 parts sophora flavescens, 10 parts kochia scoparia fruit, 10 parts dictamnus dasycarpus root bark, 10 parts artemisia capillaris, 10 parts polygonum cuspidatum, 6 parts atractylodes lancea, 10 parts poria cocos, 10 parts cynanchum paniculatum, and 10 parts peony root.

[0035] Second visit: The redness, swelling, heat and pain on the buttocks have been significantly relieved. Now, sitting down and lying down to sleep are no longer a problem.

[0036] After five more treatments, the patient recovered completely. The doctor advised the patient to avoid prolonged sitting or lying down and to abstain from spicy foods.

[0037] Case 2: Mr. Ke, medical record number: 2223****, date of visit: May 7, 2025.

[0038] Chief complaint: Redness, swelling, heat and pain at the site of progesterone injection in the right buttock for 3 days.

[0039] Present illness: In January, the patient underwent IVF-ET at our hospital. On the day of the embryo transfer, progesterone was injected intramuscularly to maintain the pregnancy for 3 months. Three days ago, without any obvious cause, the patient began to experience swelling and pain at the site of the progesterone injection on the right buttock, causing restlessness. The patient visited a maternal and child health hospital in a certain city, but was not given magnesium sulfate external application for 3 days without any significant improvement. The patient then came to our department for treatment.

[0040] Physical examination: Redness and swelling of the skin on the right side of the buttock, about 5 cm in diameter, with increased skin temperature upon touch and significant pain, but no obvious fluctuation.

[0041] Tongue and pulse characteristics: Dark red tongue, yellow coating, slippery pulse.

[0042] Diagnosis: Cellulitis of the buttock (stasis and heat accumulation).

[0043] Treatment: Clear heat and detoxify.

[0044] Prescription: Apply the Chinese herbal medicine solution to the affected area twice (once a day).

[0045] Traditional Chinese Medicine Formula (by weight): 30 parts fresh cactus, 30 parts fresh houttuynia cordata root, 15 parts honeysuckle vine, 15 parts trachelospermum jasminoides vine, 10 parts sophora flavescens, 10 parts kochia scoparia fruit, 10 parts dictamnus dasycarpus root bark, 10 parts artemisia capillaris, 10 parts polygonum cuspidatum, 6 parts atractylodes lancea, 10 parts poria cocos, 10 parts cynanchum paniculatum, 10 parts peony root. Second visit: May 7, 2025, patient reported significant relief from swelling and pain in the affected area of ​​the right buttock.

[0046] Treatment plan: Continue the above treatment for 2 more days.

[0047] Third visit: May 9, 2025, the redness and swelling on the right buttock has shrunk to 1 / 3 of its original size.

[0048] Treatment plan: Continue the above treatment for 2 more days.

[0049] Fourth consultation: On May 12, 2025, the redness, swelling, heat and pain on the right buttock were gone.

[0050] The above detailed description is a specific description of feasible embodiments of the present invention. These embodiments are not intended to limit the patent scope of the present invention. All equivalent implementations or modifications that do not depart from the present invention should be included in the patent scope of this case.

Claims

1. A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection, characterized in that, The ingredients include the following parts by weight: 20-40 parts of cactus, 20-40 parts of houttuynia cordata root, 10-20 parts of honeysuckle vine, 10-20 parts of trachelospermum jasminoides vine, 5-15 parts of sophora flavescens, 5-15 parts of kochia scoparia fruit, 5-15 parts of dictamnus dasycarpus root bark, 5-15 parts of artemisia capillaris, 8-12 parts of polygonum cuspidatum, 4-8 parts of atractylodes lancea, 8-15 parts of poria cocos, 5-15 parts of cynanchum paniculatum, and 8-12 parts of peony root.

2. The traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection according to claim 1, characterized in that, The ingredients include the following parts by weight: 30 parts cactus, 30 parts houttuynia cordata root, 15 parts honeysuckle vine, 15 parts trachelospermum jasminoides vine, 10 parts sophora flavescens, 10 parts kochia scoparia fruit, 10 parts dictamnus dasycarpus root bark, 10 parts artemisia capillaris, 10 parts polygonum cuspidatum, 6 parts atractylodes lancea, 10 parts poria cocos, 10 parts cynanchum paniculatum, and 10 parts peony root.

3. A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection according to claim 1 or 2, characterized in that, The cactus used is the fresh stem material after the thorns and skin have been removed.

4. A traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection according to claim 1 or 2, characterized in that, The houttuynia cordata root mentioned is a fresh medicinal material.

5. A method for preparing a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection as described in any one of claims 1 to 4, characterized in that, Includes the following steps: S1. Add the measured honeysuckle vine, trachelospermum jasminoides, sophora flavescens, kochia scoparia, dictamnus dasycarpus, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, poria cocos, cynanchum paniculatum, and paeonia lactiflora to water and decoct for 30-60 minutes. After filtering out the residue, continue to decoct over low heat until the liquid is concentrated into a viscous liquid. S2. Fresh cactus and houttuynia cordata roots are washed, the thorns of the cactus are removed, both are mashed and filtered, and the filtrate is evenly mixed with the viscous medicinal liquid obtained in step S1 to obtain the Chinese herbal dressing.

6. The method for preparing a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection according to claim 5, characterized in that, The following ingredients are listed: 15g of Lonicera japonica vine, 15g of Trachelospermum jasminoides vine, 10g of Sophora flavescens root, 10g of Kochia scoparia fruit, 10g of Dictamnus dasycarpus root bark, 10g of Artemisia capillaris, 10g of Polygonum cuspidatum root, 6g of Atractylodes lancea rhizome, 10g of Poria cocos, 10g of Cynanchum paniculatum root, 10g of Paeonia lactiflora root, 800mL of water, 50mL of concentrated viscous liquid, 30g of prickly pear cactus (after thorn removal), and 30g of Houttuynia cordata root.

7. A method for preparing a traditional Chinese medicine dressing for treating cellulitis caused by progesterone injection as described in any one of claims 1 to 4, characterized in that, Includes the following steps: S1. Add the measured amount of honeysuckle vine, star jasmine vine, sophora flavescens, kochia scoparia fruit, dictamnus dasycarpus root bark, artemisia capillaris, polygonum cuspidatum, atractylodes lancea, poria cocos, cynanchum paniculatum, and red peony root to hot water and stir to disperse evenly to obtain a viscous medicinal liquid. S2. Fresh cactus and houttuynia cordata roots are washed, the thorns of the cactus are removed, both are mashed and filtered, and the filtrate is evenly mixed with the viscous medicinal liquid obtained in step S1 to obtain the Chinese herbal dressing.